ApoAI recombinant protein

Recombinant Human ApoAI Protein (Fc tag)

Cat. Num. AAA173560

• Gene Names: APOA1; apo(a)
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Synonyms: ApoAI; N/A; Recombinant Human ApoAI Protein (Fc tag); APOA1, MGC117399; ApoAI recombinant protein

• Host: HEK293 Cells
• Purity/Purification: > 95 % as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5
• Sequence: Met 1-Gln 267

• Species: Human
• Tag: C-Fc
• Bio_activity: Measured by its binding ability in a functional ELISA. Immobilized Human ApoAI at 10 ug/mL (100 ul/well) can bind biotinylated human SCARB1, The EC50 of biotinylated human SCARB1 is 0.37 ug/mL.
• Endotoxin: < 1.0 EU per ug as determined by the LAL method.
• Reconstitution: Please refer to the printed manual for detailed information.
• Preparation and Storage: Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.; Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

SDS-PAGE

Related Product Information for ApoAI recombinant protein

Background: Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters, and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease.

NCBI and Uniprot Product Information

• NCBI GI #: 28772
• NCBI GeneID: 335
• Molecular Weight: Mol_Mass: 55 kDa; AP_Mol_Mass: 55 kDa
• NCBI Official Full Name: preproapolipoprotein AI
• NCBI Official Synonym Full Names: apolipoprotein A1
• NCBI Official Symbol: APOA1
• NCBI Official Synonym Symbols: apo(a)
• NCBI Protein Information: apolipoprotein A-I
• UniProt Protein Name: Apolipoprotein A-I
• UniProt Gene Name: APOA1
• UniProt Synonym Gene Names: Apo-AI; ApoA-I; ProapoA-I