SDS-PAGE
(15% SDS-PAGE using A0855-58J (3ug))
Activating Transcription Factor 3, aa1-181 Recombinant Protein | ATF3 recombinant protein
Activating Transcription Factor 3, Recombinant, Human, aa1-181 (ATF3, cAMP-dependent Transcription Factor ATF-3, Cyclic AMP-dependent Transcription Factor ATF-3)
Purity
>90% (SDS-PAGE)
Synonyms
Activating Transcription Factor 3; aa1-181; Recombinant; Human; aa1-181 (ATF3; cAMP-dependent Transcription Factor ATF-3; Cyclic AMP-dependent Transcription Factor ATF-3); ATF3 recombinant protein
Host
Recombinant corresponding to aa1-181 of human ATF3, expressed in E.coli. (NP_001665).
Purity/Purification
>90% (SDS-PAGE)
Form/Format
Supplied as a liquid in 20mM Tris-HCl, pH8.0, 2M Urea, 20% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence
MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
Grade
Highly Purified
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SDS-PAGE
(15% SDS-PAGE using A0855-58J (3ug))
SDS-PAGE
(15% SDS-PAGE using A0855-58J (3ug))
Related Product Information for ATF3 recombinant protein
ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter.
Product Categories/Family for ATF3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
~20.6kD
NCBI Official Full Name
activating transcription factor 3
NCBI Official Synonym Full Names
activating transcription factor 3
NCBI Official Symbol
ATF3
NCBI Protein Information
cyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3
UniProt Protein Name
Cyclic AMP-dependent transcription factor ATF-3
UniProt Gene Name
ATF3
UniProt Synonym Gene Names
cAMP-dependent transcription factor ATF-3
UniProt Entry Name
ATF3_HUMAN
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Product Notes
The ATF3 atf3 (Catalog #AAA14755) is a Recombinant Protein produced from Recombinant corresponding to aa1-181 of human ATF3, expressed in E.coli. (NP_001665). and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S. It is sometimes possible for the material contained within the vial of "Activating Transcription Factor 3, aa1-181, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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