SDS-PAGE
Decorin Recombinant Protein | DCN recombinant protein
Recombinant Human Decorin Protein (C-His)
Gene Names
DCN; CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Decorin; N/A; Recombinant Human Decorin Protein (C-His); Bone proteoglycan II; PG-S2; PG40; SLRR1B; DCN recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Sequence
Gly17-Lys359
Sequence Length
359
Species
Human
Reconstitution
We recommend that the vial be centrifuged to opening to bring the contents to the bottom.
Do not mix vortex.
Do not mix vortex.
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Fusion Tag
C-His
Preparation and Storage
This product is proivded as lyophilized powder which is shipped on blue ice.
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C.
Reconstituted protein solution can be stored at 4-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for up to 3 months.
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C.
Reconstituted protein solution can be stored at 4-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for up to 3 months.
SDS-PAGE
SDS-PAGE
Related Product Information for DCN recombinant protein
Protein Construction: Recombinant Human Decorin is produced by our mammalian expression system and the target gene encoding Gly17-Lys359 is expressed with a 6His tag at the C-terminus.
Background: Decorin is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). SLRP family members are characterized by N-terminal and C-terminal cysteine-rich regions which flank the central region containing 10-12 tandem leucine-rich repeats (LRR). The human Decorin cDNA encodes a 359 amino acid (aa) precursor that includes a 16 aa signal sequence and a 14 aa propeptide. Alternate splicing of human Decorin generates five isoforms with variable length deletions. Decorin is an N-glycosylated protein that also carries a variablysized hybrid chondroitin/dermatan sulfate chain at Ser34. Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors FGF2,GDF8/Myostatin, TGFbeta,and WISP1. It also binds and activates EGF R, ErbB4, and IGFI-R. In vivo, Decorin promotes myoblast differentiation, supports angiogenesis, and inhibits tumor progression.
Background: Decorin is a secreted chondroitin/dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). SLRP family members are characterized by N-terminal and C-terminal cysteine-rich regions which flank the central region containing 10-12 tandem leucine-rich repeats (LRR). The human Decorin cDNA encodes a 359 amino acid (aa) precursor that includes a 16 aa signal sequence and a 14 aa propeptide. Alternate splicing of human Decorin generates five isoforms with variable length deletions. Decorin is an N-glycosylated protein that also carries a variablysized hybrid chondroitin/dermatan sulfate chain at Ser34. Decorin regulates assembly of the extracellular collagen matrix and the bioactivity of the matrix associated growth factors FGF2,GDF8/Myostatin, TGFbeta,and WISP1. It also binds and activates EGF R, ErbB4, and IGFI-R. In vivo, Decorin promotes myoblast differentiation, supports angiogenesis, and inhibits tumor progression.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Molecular Mass: 38.8kDa
Actual Protein Molecular Mass: 43-50kDa
Actual Protein Molecular Mass: 43-50kDa
NCBI Official Full Name
Decorin
NCBI Official Synonym Full Names
decorin
NCBI Official Symbol
DCN
NCBI Official Synonym Symbols
CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
NCBI Protein Information
decorin
UniProt Protein Name
Decorin
UniProt Gene Name
DCN
UniProt Synonym Gene Names
SLRR1B
UniProt Entry Name
PGS2_HUMAN
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Product Notes
The DCN dcn (Catalog #AAA174704) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gly17-Lys3 59. It is sometimes possible for the material contained within the vial of "Decorin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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