Type III iodothyronine deiodinase (dio3) Recombinant Protein | dio3 recombinant protein
Recombinant Xenopus laevis Type III iodothyronine deiodinase (dio3), partial
Gene Names
dio3.L; D3; DI-3; dio3; 5DIII; XL-15; itdi3; txdi3; DIOIII
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Type III iodothyronine deiodinase (dio3); N/A; Recombinant Xenopus laevis Type III iodothyronine deiodinase (dio3), partial; dio3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
37-271.(U132S) Partial, provide the complete extracellular domain.
Sequence
DFQCIRRRVLLTAREESTAEHEDPPLCVSDSNRMCTVESLRAVWHGQKLDYFKSAHLGCSAPNTEVVMLEGRRLCKILDFSQGKRPLVVNFGSCTSPPFMARLQAYRRLAAQHVGIADFLLVYIEEAHPSDGWLSTDASYQIPQHQCLQDRLAAAQLMLQGAPGCRVVVDTMDNSSNAAYGAYFERLYIVLEGKVVYQGGRGPEGYKISELRMWLEQYQQGLMGTKGSGQVVIQV
Sequence Length
271
Species
Xenopus laevis (African clawed frog)
Buffer
Tris-based buffer, 50% glycerol
Notes
The amino acid at position 132 is originally a "U", which has already been mutated to be "S" in the above sequence. This is due to the "U", or selenocysteine, which is encoded by UGA, is normally used as a stop codon in prokaryotic cells. Thus leading to early termination of translation. So we have substituted this "U" to simply be an "S" so that translation can proceed. Changing to cysteine may result in undesired disulfide bond formation, so serine is chosen since it is structurally related to both selenocysteine and cysteine.
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
thyroxine 5-deiodinase
NCBI Official Synonym Full Names
deiodinase, iodothyronine, type 3 L homeolog
NCBI Official Symbol
dio3.L
NCBI Official Synonym Symbols
D3; DI-3; dio3; 5DIII; XL-15; itdi3; txdi3; DIOIII
NCBI Protein Information
thyroxine 5-deiodinase L homeolog
UniProt Protein Name
Thyroxine 5-deiodinase
UniProt Gene Name
dio3
UniProt Synonym Gene Names
itdi3; txdi3
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Product Notes
The dio3 dio3 (Catalog #AAA115491) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 37-271.(U132S) Partial, provide the complete extracellular domain. The amino acid sequence is listed below: DFQCIRRRVL LTAREESTAE HEDPPLCVSD SNRMCTVESL RAVWHGQKLD YFKSAHLGCS APNTEVVMLE GRRLCKILDF SQGKRPLVVN FGSCTSPPFM ARLQAYRRLA AQHVGIADFL LVYIEEAHPS DGWLSTDASY QIPQHQCLQD RLAAAQLMLQ GAPGCRVVVD TMDNSSNAAY GAYFERLYIV LEGKVVYQGG RGPEGYKISE LRMWLEQYQQ GLMGTKGSGQ VVIQV. It is sometimes possible for the material contained within the vial of "Type III iodothyronine deiodinase (dio3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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