Activin-A Active Protein | INHBA active protein

Recombinant Human Activin-A, Active

Cat. Num. AAA38992

• Gene Names: INHBA; EDF; FRP
• Purity: Greater than 95% as obsereved by SDS-PAGE.
• Synonyms: Activin-A; N/A; Recombinant Human Activin-A, Active; Inhba, Inhibin beta A, FSH releasing protein.; INHBA active protein

• Host: E Coli
• Purity/Purification: Greater than 95% as obsereved by SDS-PAGE.
• Form/Format: Human Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 0.1% TFA.
• Sequence: MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS
• Sequence Length: 426

• Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Solubility: Human INHBA protein should be reconstituted in distilled pyrogen free water to a concentration of 100ug /ml which can then be further diluted to other aqueous solutions.
• Biological Activity: Biological activity is assessed by the ability to induce cytoxicity of MPC-11 cells and was found to be 8.8ng/ml corresponding to a specific activity of 1.1x10⁵ units/mg.
• Preparation and Storage: Lyophilized Activin-A although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Activin-A should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Related Product Information for INHBA active protein

Description: Active form Activin-A Human Recombinant produced in E Coli is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 117 amino acids and having a molecular weight of 26.2kDa.The Active form Activin-A is purified by standard chromatographic techniques.

Introduction: Activins are homodimers or heterodimers of the different beta subunit isoforms, part of the TGFbeta family. Mature Activin A has two 116 amino acids residues betaA subunits (betaA-betaA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.

Product Categories/Family for INHBA active protein

Cytokines and Growth Factors; Growth Factors; Activin

NCBI and Uniprot Product Information

• NCBI GI #: 4504699
• NCBI GeneID: 3624
• NCBI Accession #: NP_002183.1
• NCBI GenBank Nucleotide #: NM_002192.2
• UniProt Accession #: P08476; Q14599
• NCBI Official Full Name: inhibin beta A chain
• NCBI Official Synonym Full Names: inhibin, beta A
• NCBI Official Symbol: INHBA
• NCBI Official Synonym Symbols: EDF; FRP
• NCBI Protein Information: inhibin beta A chain; FSH-releasing protein; Inhibin, beta-1; activin beta-A chain; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; inhibin, beta A (activin A, activin AB alpha polypeptide)
• UniProt Protein Name: Inhibin beta A chain
• UniProt Gene Name: INHBA
• UniProt Synonym Gene Names: EDF
• UniProt Entry Name: INHBA_HUMAN