Apo-SAA active protein
Human Apo-SAA
Gene Names
SAA1; SAA; PIG4; SAA2; TP53I4
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Synonyms
Apo-SAA; N/A; Human Apo-SAA; Recombinant Human Apo-SAA; Apo-SAA active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 98% by SDS-PAGE and HPLC analyses
Form/Format
Lyophilized (5mM Tris, pH7.8)
Sequence
MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAA KRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG K DPNHFRPAG LPEKY
Sequence Length
122
Endotoxin Level
< 0.1 ng /ug of protein (<1EU/ug).
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containinga carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C
Length
104
Biological Activity
Tested by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 uM.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 6 months at -20°C to -80°C. Avoid repeated freeze and thaw cycles.
Related Product Information for Apo-SAA active protein
Human Apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of Apo-SAA, normally 1-5 ug/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL Apolipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence. Recombinant Apo-SAA is a consensus SAA molecule corresponding to human Apo-SAA1alpha except for the presence of an N-terminal methionine and substitution of asparagine for aspartic acid at position 60 and arginine for histidine at position 71(the last two substituted residues are present in apo-SAA2beta). The calculated molecular weight of recombinant human Apo-SAA is 11.4 kDa.
Product Categories/Family for Apo-SAA active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11.4 kDa
NCBI Official Full Name
serum amyloid A-1 protein preproprotein
NCBI Official Synonym Full Names
serum amyloid A1
NCBI Official Symbol
SAA1
NCBI Official Synonym Symbols
SAA; PIG4; SAA2; TP53I4
NCBI Protein Information
serum amyloid A-1 protein; serum amyloid A protein; tumor protein p53 inducible protein 4
UniProt Protein Name
Serum amyloid A-1 protein
UniProt Gene Name
SAA1
UniProt Synonym Gene Names
SAA
UniProt Entry Name
SAA1_HUMAN
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Product Notes
The Apo-SAA saa1 (Catalog #AAA14951) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human Apo-SAA reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAA KRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG K DPNHFRPAG LPEKY. It is sometimes possible for the material contained within the vial of "Apo-SAA, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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