ApoE3 active protein
Human ApoE3
Gene Names
APOE; AD2; LPG; LDLCQ5
Reactivity
Human
Purity
> 90% by SDS-PAGE and HPLC analyses
Synonyms
ApoE3; N/A; Human ApoE3; Recombinant Human ApoE3; ApoE3 active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 90% by SDS-PAGE and HPLC analyses
Form/Format
Lyophilized (20mM Sodium Phosphat, pH 7.8)
Sequence
MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSE QVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET R ARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVR LAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RL GPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRD RL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDM QRQWAGL VEKVQAAVGT SAAPVPSDNH
Sequence Length
317
Endotoxin Level
< 0.1 ng/ug of protein (<1EU/?g).
Length (aa)
300
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. NOTE: Allow the reconstituted vial to sit at room temperature for 1 hour before use. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Related Product Information for ApoE3 active protein
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Individuals heterozygous for the ApoE4 allele are at higher risk of late-onset Alzheimer’s disease. Recombinant human ApoE4 is a 34.4 kDa protein containing 300 amino acid residues.
Product Categories/Family for ApoE3 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34.4 kDa
NCBI Official Full Name
apolipoprotein E
NCBI Official Synonym Full Names
apolipoprotein E
NCBI Official Symbol
APOE
NCBI Official Synonym Symbols
AD2; LPG; LDLCQ5
NCBI Protein Information
apolipoprotein E; apo-E; apolipoprotein E3
UniProt Protein Name
Apolipoprotein E
UniProt Gene Name
APOE
UniProt Synonym Gene Names
Apo-E
UniProt Entry Name
APOE_HUMAN
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Product Notes
The ApoE3 apoe (Catalog #AAA79280) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human ApoE3 reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSE QVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET R ARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVR LAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RL GPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRD RL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDM QRQWAGL VEKVQAAVGT SAAPVPSDNH. It is sometimes possible for the material contained within the vial of "ApoE3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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