SDS-PAGE
Cathepsin S Active Protein | Ctss active protein
Recombinant Mouse Cathepsin S Protein
Gene Names
Ctss; Cats
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Cathepsin S; N/A; Recombinant Mouse Cathepsin S Protein; CTSS; Ctss active protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence
Val18-IIe340
Sequence Length
340
Species
Mouse
Endotoxin
<1.0 EU per mug as determined by LAL test.
Fragment
Met 1-Ile 340
Tag
C-6His
Activity
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVENval-WRK (Dnp)-NH2, AnaSpec, Catalog # 27114.The specific activity is >300 pmoles/min/mug.(Activation description: The enzyme achieves its activity under acidic pH)
Reconstitution
We recommend that the vial be centrifuged to opening to bring the contents to the bottom. Do not mix by vortex.
It is recommended that steile water be added to the vial to prepare a stock solution of 0.25mg/mL. Concentration is mesured by UV-Vis.
It is recommended that steile water be added to the vial to prepare a stock solution of 0.25mg/mL. Concentration is mesured by UV-Vis.
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
SDS-PAGE
SDS-PAGE
Related Product Information for Ctss active protein
Background: Cathepsin S is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, cathepsin S is expressed in some epithelial cells. Compared with the abundant cathepsins B, L and H, cathepsin S shows a restricted tissue distribution, with highest levels in spleen, heart, and lung. In addition, evidences indicated that cathepsin S generates A beta from amyloidogenic fragments of beta APP in the endosomal/lysosomal compartment, and is implicated in the pathogenesis of Alzheimer's disease (AD) and Down Syndrome (DS).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Molecular Mass: 37.5kDa
Actual Protein Molecular Mass: 37 & 28-32 & 14kDa
Actual Protein Molecular Mass: 37 & 28-32 & 14kDa
NCBI Official Full Name
cathepsin S
NCBI Official Synonym Full Names
cathepsin S
NCBI Official Symbol
Ctss
NCBI Official Synonym Symbols
Cats
NCBI Protein Information
cathepsin S
UniProt Protein Name
Cathepsin S
UniProt Gene Name
Ctss
UniProt Synonym Gene Names
Cats
Similar Products
Product Notes
The Ctss ctss (Catalog #AAA174601) is an Active Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Val18-IIe3 40. It is sometimes possible for the material contained within the vial of "Cathepsin S, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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