Pepsinogen II Active Protein | PGC active protein
Pepsinogen II (PGII/PGC), Human Gastric Mucosa
Gene Names
PGC; PEPC; PGII
Applications
Western Blot
Purity
>90% (SDS-PAGE) may contain minor cleavage products.
Synonyms
Pepsinogen II; N/A; Pepsinogen II (PGII/PGC), Human Gastric Mucosa; Pepsinogen C; PG II; PGC; Gastricsin; Pepsinogen II (PGII, PGC) - >=90% (SDS-PAGE) - Lyophilized; PGC active protein
Host
Human gastric mucosa
Purity/Purification
>90% (SDS-PAGE) may contain minor cleavage products.
Form/Format
Powder, lyophilized from tris chloride, pH 8.5
Sequence Length
315
Applicable Applications for PGC active protein
WB (Western Blot)
Appearance
White to off-white powder.
Solubility
Clear, colorless (1mg/mL 0.02 M Tris-Chloride, pH= 8.0 buffer)
Protein
1.4 mg protein /vial (E 0.1%280nm= 1.43)
Specific Activity
2,920 U/mg protein (after activation)
Unit Definition
One unit will produce a change in A280 of 0.001 per minute at pH 2.0 and 37°C, measured as TCA-soluble products from hemoglobin.
Identity
Confirmed by Western Blot.
Handling
Handle as a potentially hazardous substance
Reconstitution
After reconstitution maintain at or above pH 8.0 to avoid activation.
Preparation and Storage
Store at -20°C.
Related Product Information for PGC active protein
AAA Biotech is the leading producer and supplier of Human Pepsinogen II/C antigen as a stomach gastric cancer marker for medical research, clinical and manufacturing.
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of porteins after activation of acidic pH. Pepsinogen is synthesized as isoymogens and are classified into two groups, I and II.
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Pepsinogens are aspartic proteases produced in the gastric mucosa and secreted into the gastric lumen that play a major role in the digestion of porteins after activation of acidic pH. Pepsinogen is synthesized as isoymogens and are classified into two groups, I and II.
Product Categories/Family for PGC active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
40,600
NCBI Official Full Name
Gastricsin
NCBI Official Synonym Full Names
progastricsin (pepsinogen C)
NCBI Official Symbol
PGC
NCBI Official Synonym Symbols
PEPC; PGII
NCBI Protein Information
gastricsin; pepsin C; pepsinogen C; preprogastricsin; pepsinogen group II
UniProt Protein Name
Gastricsin
UniProt Gene Name
PGC
UniProt Entry Name
PEPC_HUMAN
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Product Notes
The PGC pgc (Catalog #AAA44860) is an Active Protein produced from Human gastric mucosa and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Pepsinogen II can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the PGC pgc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pepsinogen II, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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