SDS-PAGE
(Recombinant Human IL-28A/IL28A Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 20-23 kDa.)
IL-28A/IL28A recombinant protein
Recombinant Human IL-28A/IL28A Protein
Gene Names
IFNL2; IL28A; IL-28A
Purity
>97% by SDS-PAGE.
Synonyms
IL-28A/IL28A; N/A; Recombinant Human IL-28A/IL28A Protein; IL-28A; IL28A; ZCYTO20; IL-28A/IL28A recombinant protein
Host
HEK293 cells
Purity/Purification
>97% by SDS-PAGE.
Form/Format
Lyophilized from a 0.22um filtered solution of PBS, pH7.4.
Species
Human
Endotoxin
<0.1EU/ug of the protein by LAL method.
Tag
C-His
Reconstitution
Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Preparation and Storage
Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
SDS-PAGE
(Recombinant Human IL-28A/IL28A Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 20-23 kDa.)
SDS-PAGE
(Recombinant Human IL-28A/IL28A Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 20-23 kDa.)
Related Product Information for IL-28A/IL28A recombinant protein
Recombinant Human IL-28A/IL28A Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val26-Val200) of human IL-28A/IL28A (Accession #NP_742150.1) fused with a 6×His tag at the C-terminus.
Background: IL 28A (Interferon-lambda 2; IFN-lambda 2), IL-28B/IFN-lambda 3, and IL-29/IFN-lambda 1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. IL 28A, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine which are expression can be induced by viral infection.In the liver, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
Background: IL 28A (Interferon-lambda 2; IFN-lambda 2), IL-28B/IFN-lambda 3, and IL-29/IFN-lambda 1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. IL 28A, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine which are expression can be induced by viral infection.In the liver, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast, it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
Product Categories/Family for IL-28A/IL28A recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,288 Da
NCBI Official Full Name
interferon lambda-2
NCBI Official Synonym Full Names
interferon, lambda 2
NCBI Official Symbol
IFNL2
NCBI Official Synonym Symbols
IL28A; IL-28A
NCBI Protein Information
interferon lambda-2; IFN-lambda-2; interleukin-28A; cytokine Zcyto20; interferon lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2)
UniProt Protein Name
Interferon lambda-2
UniProt Gene Name
IFNL2
UniProt Synonym Gene Names
IL28A; ZCYTO20; IFN-lambda-2; IL-28A
UniProt Entry Name
IFNL2_HUMAN
Similar Products
Product Notes
The IL-28A/IL28A ifnl2 (Catalog #AAA282162) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IL-28A/IL28A, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.