SDS-PAGE
DNA replication licensing factor MCM2 Recombinant Protein | MCM2 recombinant protein
Recombinant Human DNA replication licensing factor MCM2 (MCM2)
Gene Names
MCM2; BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
DNA replication licensing factor MCM2; Recombinant Human DNA replication licensing factor MCM2 (MCM2); Minichromosome maintenance protein 2 homolog; Nuclear protein BM28; MCM2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-904aa; Full Length of Mature Protein
Sequence
AESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDEDVEELTASQREAAERAMRQRDREAGRGLGRMRRGLLYDSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLSFRRDNNELLLFILKQLVAEQVTYQRNRFGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSELFRMNKFSHDLKRKMILQQF
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for MCM2 recombinant protein
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
Product Categories/Family for MCM2 recombinant protein
References
A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division.Todorov I.T., Pepperkok R., Philipova R.N., Kearsey S.E., Ansorge W., Werner D.J. Cell Sci. 107:253-265(1994)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
105.8 kDa
NCBI Official Full Name
DNA replication licensing factor MCM2
NCBI Official Synonym Full Names
minichromosome maintenance complex component 2
NCBI Official Symbol
MCM2
NCBI Official Synonym Symbols
BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN
NCBI Protein Information
DNA replication licensing factor MCM2
UniProt Protein Name
DNA replication licensing factor MCM2
UniProt Gene Name
MCM2
UniProt Synonym Gene Names
BM28; CCNL1; CDCL1; KIAA0030
UniProt Entry Name
MCM2_HUMAN
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Product Notes
The MCM2 mcm2 (Catalog #AAA18445) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-904aa; Full Length of Mature Protein. The amino acid sequence is listed below: AESSESFTMA SSPAQRRRGN DPLTSSPGRS SRRTDALTSS PGRDLPPFED ESEGLLGTEG PLEEEEDGEE LIGDGMERDY RAIPELDAYE AEGLALDDED VEELTASQRE AAERAMRQRD REAGRGLGRM RRGLLYDSDE EDEERPARKR RQVERATEDG EEDEEMIESI ENLEDLKGHS VREWVSMAGP RLEIHHRFKN FLRTHVDSHG HNVFKERISD MCKENRESLV VNYEDLAARE HVLAYFLPEA PAELLQIFDE AALEVVLAMY PKYDRITNHI HVRISHLPLV EELRSLRQLH LNQLIRTSGV VTSCTGVLPQ LSMVKYNCNK CNFVLGPFCQ SQNQEVKPGS CPECQSAGPF EVNMEETIYQ NYQRIRIQES PGKVAAGRLP RSKDAILLAD LVDSCKPGDE IELTGIYHNN YDGSLNTANG FPVFATVILA NHVAKKDNKV AVGELTDEDV KMITSLSKDQ QIGEKIFASI APSIYGHEDI KRGLALALFG GEPKNPGGKH KVRGDINVLL CGDPGTAKSQ FLKYIEKVSS RAIFTTGQGA SAVGLTAYVQ RHPVSREWTL EAGALVLADR GVCLIDEFDK MNDQDRTSIH EAMEQQSISI SKAGIVTSLQ ARCTVIAAAN PIGGRYDPSL TFSENVDLTE PIISRFDILC VVRDTVDPVQ DEMLARFVVG SHVRHHPSNK EEEGLANGSA AEPAMPNTYG VEPLPQEVLK KYIIYAKERV HPKLNQMDQD KVAKMYSDLR KESMATGSIP ITVRHIESMI RMAEAHARIH LRDYVIEDDV NMAIRVMLES FIDTQKFSVM RSMRKTFARY LSFRRDNNEL LLFILKQLVA EQVTYQRNRF GAQQDTIEVP EKDLVDKARQ INIHNLSAFY DSELFRMNKF SHDLKRKMIL QQF . It is sometimes possible for the material contained within the vial of "DNA replication licensing factor MCM2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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