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Application Data
(Anti-IL-31Ra Reference Antibody (nemolizumab) Activation inhibition was evaluated using Hacat. The max induction fold was approximately 1.86.)
IL-31Ra recombinant antibody
Anti-IL-31Ra Reference Antibody (nemolizumab)
Gene Names
IL31RA; CRL; GPL; CRL3; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384
Reactivity
Human, Cynomolgus
Applications
ELISA, Flow Cytometry, Functional Assay, Functional Assay
Synonyms
IL-31Ra, Recombinant Antibody; Anti-IL-31Ra Reference Antibody (nemolizumab); IL-31Ra recombinant antibody
Host
CHO Cell
Reactivity
Human, Cynomolgus
Clonality
Monoclonal
Isotype
IgG2SA
Specificity
IL-31Ra
Form/Format
Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.This antibody is purified through a protein A column.
Concentration
1mg/ml (varies by lot)
Applicable Applications for IL-31Ra recombinant antibody
ELISA (EIA), Flow Cytometry (FC/FACS), Kinetics, Functional Assay (FUNC), Animal Model
Endotoxin
< 0.001EU/ug, determined by LAL method.
Conjugation
Unconjugated
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -80 degree C for 2 years under sterile conditions; -20 degree C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
Application Data
(Anti-IL-31Ra Reference Antibody (nemolizumab) Activation inhibition was evaluated using Hacat. The max induction fold was approximately 1.86.)
Application Data
(Anti-IL-31Ra Reference Antibody (nemolizumab) Activation inhibition was evaluated using Hacat. The max induction fold was approximately 1.86.)
Application Data
(Anti-IL-31Ra Reference Antibody (nemolizumab) P-STAT3 Assay was evaluated using Du145. The IC50 was approximately 0.1068 ug/ml.)
Application Data
(Anti-IL-31Ra Reference Antibody (nemolizumab) P-STAT3 Assay was evaluated using Du145. The IC50 was approximately 0.1068 ug/ml.)
FCM (Flow Cytometry)
(Human IL31R HEK293 cells were stained with Anti-IL-31Ra Reference Antibody (nemolizumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC181=0.307 ug/mL)
FCM (Flow Cytometry)
(Human IL31R HEK293 cells were stained with Anti-IL-31Ra Reference Antibody (nemolizumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC181=0.307 ug/mL)
Application Data
(Immobilized human IL31R His at 2 ug/mL can bind Anti-IL-31Ra Reference Antibody (nemolizumab), EC50=0.0153ug/mL)
Application Data
(Immobilized human IL31R His at 2 ug/mL can bind Anti-IL-31Ra Reference Antibody (nemolizumab), EC50=0.0153ug/mL)
Application Data
(The purity of Anti-IL-31Ra Reference Antibody (nemolizumab)is more than 100% ,determined by SEC-HPLC.)
Application Data
(The purity of Anti-IL-31Ra Reference Antibody (nemolizumab)is more than 100% ,determined by SEC-HPLC.)
SDS-PAGE
(Anti-IL-31Ra Reference Antibody (nemolizumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)
SDS-PAGE
(Anti-IL-31Ra Reference Antibody (nemolizumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)
Product Categories/Family for IL-31Ra recombinant antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84,309 Da
NCBI Official Full Name
interleukin-31 receptor subunit alpha isoform 2
NCBI Official Synonym Full Names
interleukin 31 receptor A
NCBI Official Symbol
IL31RA
NCBI Official Synonym Symbols
CRL; GPL; CRL3; GLMR; GLM-R; PLCA2; hGLM-R; IL-31RA; PRO21384
NCBI Protein Information
interleukin-31 receptor subunit alpha
UniProt Protein Name
Interleukin-31 receptor subunit alpha
UniProt Gene Name
IL31RA
UniProt Synonym Gene Names
CRL3; GPL; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; hGLM-R; Gp130-like receptor
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Product Notes
The IL-31Ra il31ra (Catalog #AAA29396) is a Recombinant Antibody produced from CHO Cell and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL-31Ra Reference Antibody (nemolizumab) reacts with Human, Cynomolgus and may cross-react with other species as described in the data sheet. AAA Biotech's IL-31Ra can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS), Kinetics, Functional Assay (FUNC), Animal Model. Researchers should empirically determine the suitability of the IL-31Ra il31ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-31Ra, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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