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IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse stomach using ACVR1C antibody at dilution of 1:100 (40x lens).)
Rabbit ACVR1C Polyclonal Antibody | anti-ACVR1C antibody
ACVR1C Polyclonal Antibody
Gene Names
ACVR1C; ALK7; ACVRLK7
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purification
Synonyms
ACVR1C, Antibody; ACVR1C Polyclonal Antibody; ACVR1C; ACVRLK7; ALK7; anti-ACVR1C antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Sequence Length
493
Applicable Applications for anti-ACVR1C antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500 - 1:2000
IHC: 1:10 - 1:200
IHC: 1:10 - 1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-113 of human ACVR1C (NP_660302.2).
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse stomach using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse stomach using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistchemistry)
(Immunohistochemistry of paraffin-embedded mouse kidney using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistchemistry)
(Immunohistochemistry of paraffin-embedded mouse kidney using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse brain using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse brain using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse lung using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded mouse lung using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human stomach using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human stomach using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded rat brain using ACVR1C antibody at dilution of 1:100 (40x lens).)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded rat brain using ACVR1C antibody at dilution of 1:100 (40x lens).)
WB (Western Blot)
(Western blot analysis of extracts of SH-SY5Y cells, using ACVR1C antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)
WB (Western Blot)
(Western blot analysis of extracts of SH-SY5Y cells, using ACVR1C antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)
Related Product Information for anti-ACVR1C antibody
ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. (Bondestam et al., 2001[PubMed 12063393]).
Product Categories/Family for anti-ACVR1C antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Calculated MW: 37kDa/46kDa/49kDa/54kDa
Observed MW: 60kDa
Observed MW: 60kDa
NCBI Official Full Name
Activin receptor type-1C
NCBI Official Synonym Full Names
activin A receptor, type IC
NCBI Official Symbol
ACVR1C
NCBI Official Synonym Symbols
ALK7; ACVRLK7
NCBI Protein Information
activin receptor type-1C; ALK-7; ACVR1C; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7
UniProt Protein Name
Activin receptor type-1C
UniProt Gene Name
ACVR1C
UniProt Synonym Gene Names
ACTR-IC; ALK-7
UniProt Entry Name
ACV1C_HUMAN
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Product Notes
The ACVR1C acvr1c (Catalog #AAA10695) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACVR1C Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ACVR1C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500 - 1:2000 IHC: 1:10 - 1:200. Researchers should empirically determine the suitability of the ACVR1C acvr1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACVR1C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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