Rabbit BAX Polyclonal Antibody | anti-BAX antibody
BAX Polyclonal Antibody
Gene Names
                                                    BAX; BCL2L4
                                                Reactivity
                                                    Human, Mouse, Rat
                                                Applications
                                                    Western Blot, Immunofluorescence
                                                Purity
                                                    Affinity purification
                                                Synonyms
                                            BAX, Antibody; BAX Polyclonal Antibody; BAX; BCL2L4; apoptosis regulator BAX; anti-BAX antibody
                                        
                    Host                
                
                    Rabbit                
            
                    Reactivity                
                
                    Human, Mouse, Rat                
            
                    Clonality                
                
                    Polyclonal                
            
                    Isotype                
                
                    IgG                
            
                    Purity/Purification                
                
                    Affinity purification                
            
                    Form/Format                
                
                    PBS with 50% glycerol, pH7.4                
            
                    Sequence Length                
                
                    192                
            
                    Applicable Applications for anti-BAX antibody                
                
                    Western Blot (WB), Immunofluorescence (IF)                
            
                    Application Notes                
                
                    WB: 1:500-1:1000
IF: 1:50-1:100
            IF: 1:50-1:100
                        Immunogen                    
                    
                        Recombinant fusion protein of human BAX (NP_620116.1).                    
                
                        Conjugation                    
                    
                        Unconjugated                    
                
                    Preparation and Storage                
                
                    Store at -20 degree C. Avoid freeze/thaw cycles.                
            WB (Western Blot)
(Western blot analysis of extracts from normal (control) and BAX knockout (KO) 293T cells, using BAX antibody.)
                    Related Product Information for anti-BAX antibody                
                
                 
                    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.                 
                
            
                    Product Categories/Family for anti-BAX antibody                
                
            NCBI and Uniprot Product Information
                    NCBI GI #                
                
            
                    NCBI GeneID                
                
            
                    NCBI Accession #                
                
            
                    NCBI GenBank Nucleotide #                
                
            
                    UniProt Accession #                
                
            
                    Molecular Weight                
                
                                            23kDa                                    
            
                    NCBI Official Full Name                
                
                    apoptosis regulator BAX isoform alpha                
            
                    NCBI Official Synonym Full Names                
                
                    BCL2 associated X, apoptosis regulator                
            
                    NCBI Official Symbol                
                
                    BAX                 
            
                    NCBI Official Synonym Symbols                
                
                    BCL2L4                 
            
                    NCBI Protein Information                
                
                    apoptosis regulator BAX                
            
                    UniProt Protein Name                
                
                    Apoptosis regulator BAX                
            
                    UniProt Gene Name                
                
                    BAX                
            
                    UniProt Synonym Gene Names                
                
                    BCL2L4; Bcl2-L-4                
            
                    UniProt Entry Name                
                
                    BAX_HUMAN                
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Product Notes
The BAX bax (Catalog #AAA29799) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BAX Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BAX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:1000 IF: 1:50-1:100. Researchers should empirically determine the suitability of the BAX bax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BAX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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