IHC (Immunohiostchemistry)
(CACNG8 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CACNG8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human, Mouse CACNG8 Polyclonal Antibody | anti-CACNG8 antibody
CACNG8 Antibody (N-term)
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CACNG8, Antibody; CACNG8 Antibody (N-term); Voltage-dependent calcium channel gamma-8 subunit; Neuronal voltage-gated calcium channel gamma-8 subunit; Transmembrane AMPAR regulatory protein gamma-8; TARP gamma-8; CACNG8; CACNG6; anti-CACNG8 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
This CACNG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of human CACNG8.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
90-119
Applicable Applications for anti-CACNG8 antibody
IHC (Immunohistochemistry-Paraffin), ELISA, WB (Western Blot)
Application Notes
WB~~1:1000; IHC-P~~1:10~50; E~~Use at an assay dependent concentration.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CACNG8 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CACNG8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CACNG8 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CACNG8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CACNG8 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CACNG8 antibody detected the CACNG8 protein (arrow).)
WB (Western Blot)
(CACNG8 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CACNG8 antibody detected the CACNG8 protein (arrow).)
Related Product Information for anti-CACNG8 antibody
Function Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.
Cellular Location: Cell membrane {ECO:0000250|UniProtKB:Q8VHW2}; Multi-pass membrane protein. Postsynaptic density membrane {ECO:0000250|UniProtKB:Q8VHW2}
Tissue Location: Detected in heart left ventricle.
Cellular Location: Cell membrane {ECO:0000250|UniProtKB:Q8VHW2}; Multi-pass membrane protein. Postsynaptic density membrane {ECO:0000250|UniProtKB:Q8VHW2}
Tissue Location: Detected in heart left ventricle.
Product Categories/Family for anti-CACNG8 antibody
References
Sager, C., et al. Neuroscience 158(1):45-54(2009)
Correia, S.S., et al. Nat. Neurosci. 11(4):457-466(2008)
Chen, R.S., et al. Cell Biochem. Biophys. 47(2):178-186(2007)
Chu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :
Burgess, D.L., et al. Genomics 71(3):339-350(2001)
Correia, S.S., et al. Nat. Neurosci. 11(4):457-466(2008)
Chen, R.S., et al. Cell Biochem. Biophys. 47(2):178-186(2007)
Chu, P.J., et al. Gene 280 (1-2), 37-48 (2001) :
Burgess, D.L., et al. Genomics 71(3):339-350(2001)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
voltage-dependent calcium channel gamma-8 subunit
NCBI Official Synonym Full Names
calcium channel, voltage-dependent, gamma subunit 8
NCBI Official Symbol
CACNG8
NCBI Protein Information
voltage-dependent calcium channel gamma-8 subunit
UniProt Protein Name
Voltage-dependent calcium channel gamma-8 subunit
UniProt Gene Name
CACNG8
UniProt Synonym Gene Names
CACNG6; TARP gamma-8
UniProt Entry Name
CCG8_HUMAN
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Product Notes
The CACNG8 cacng8 (Catalog #AAA287415) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 90-119. The CACNG8 Antibody (N-term) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CACNG8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry-Paraffin), ELISA, WB (Western Blot). WB~~1:1000; IHC-P~~1:10~50; E~~Use at an assay dependent concentration. Researchers should empirically determine the suitability of the CACNG8 cacng8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CACNG8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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