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Application Data

anti-Mouse GM-CSF-R-alpha Polyclonal Antibody | anti-GM-CSF-R-alpha antibody

GM-CSF-R-alpha (CD116) Antibody

Gene Names
Csf2ra; CD116; Csfgmra; GM-CSFR; GM-CSF-Ra
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry
Purity
Affinity purified
Synonyms
GM-CSF-R-alpha, Antibody; GM-CSF-R-alpha (CD116) Antibody; anti-GM-CSF-R-alpha antibody
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For Research Use Only!
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of mouse GM-CSF-R-alpha.
Purity/Purification
Affinity purified
Form/Format
1*TBS (pH7.4), 0.5%BSA, 25% Glycerol.
Sequence Length
388
Applicable Applications for anti-GM-CSF-R-alpha antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
WB: 1:1000
Preservative
0.05% Sodium Azide.
Cellular Localization
Cell Membrane
Positive Control
F9
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.

Application Data

(Fig: Western blot analysis on F9 cell lysates using anti- GM-CSF-R-alpha polyclonal antibody.)

Related Product Information for anti-GM-CSF-R-alpha antibody
The granulocyte macrophage-colony-stimulating factor receptor (GM-CSF-R) is a heterodimer composed of 2 subunits, alphaand beta, and ligand binding to the high-affinity receptor leads to signalling for the multiple actions of GM-CSF on target cells. The GM-CSF receptors are found on the surface of myeloid precursors, granulocytes, mononuclear phagocyte, and also frequently present on the myeloid malignancies. The GM-CSF-R-alpha transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
References
1. Lanza F, Moretti S, Papa S, et al. Report on the fifth interna tional workshop on human leukocyte differentiation antigens. Boston, November 3-7, 1993, Haematologica, 1994, 79:374-386. 2. Lanza F, Castagnar B, Rigolin G, et al. Flow cytometry measurement of GM-CSF receptors in acute leukemic blasts, and normal hemopoietic cells. Leukem ia, 1997, 11: 1700-1710. 3. Jubinsky P T, Laurie A S, Nathan D G, et al. Expression and function of the human granulocyte-macrophage colony-stimulating factor receptor alpha sub unit. Blood, 1994, 84:4174-4185.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70; 42kDa
NCBI Official Full Name
granulocyte-macrophage colony-stimulating factor receptor subunit alpha
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
NCBI Official Symbol
Csf2ra
NCBI Official Synonym Symbols
CD116; Csfgmra; GM-CSFR; GM-CSF-Ra
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor receptor subunit alpha
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
UniProt Gene Name
Csf2ra
UniProt Synonym Gene Names
Csfgmra; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha

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Product Notes

The GM-CSF-R-alpha csf2ra (Catalog #AAA17988) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The GM-CSF-R-alpha (CD116) Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GM-CSF-R-alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). WB: 1:1000. Researchers should empirically determine the suitability of the GM-CSF-R-alpha csf2ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GM-CSF-R-alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.