Rabbit anti-Human, Mouse IFIH1 / MDA5 Polyclonal Antibody | anti-IFIH1 antibody

Rabbit Polyclonal to Human IFIH1 / MDA5

Cat. Num. AAA12315

• Gene Names: IFIH1; AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: IFIH1 / MDA5, Antibody; Rabbit Polyclonal to Human IFIH1 / MDA5; Anti-IFIH1 / MDA5 Antibody (C-Terminus) IHC-plus; IFIH1; Helicase with 2 CARD domains; MDA-5; MDA5; Helicard; IDDM19; RLR-2; RH116; CADM-140 autoantigen; Hlcd; RIG-I-like receptor 2; Human IFIH1; anti-IFIH1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: 16 amino acid peptide from near the carboxy terminus of human MDA5.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 1025

• Applicable Applications for anti-IFIH1 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 ug/ml), WB (4 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues and a panel of mouse tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After inc...
• Target Species: Human
• Immunogen Description: Synthetic peptide from human IFIH1 / MDA5.
• Immunogen Type: Synthetic peptide
• Immunogen: IFIH1 / MDA5 antibody was raised against synthetic peptide from human IFIH1 / MDA5.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

WB (Western Blot)

(Western blot of MDA5 in Daudi cell lysate with MDA5 antibody at (A) 1, (B) 2 and (C) 4 ug/ml.)

IF (Immunofluorescence)

(Immunofluorescence of MDA5 in Human Lymph Node cells with MDA5 antibody at 20 ug/ml.)

IHC (Immunohistochemistry)

(Anti-MDA5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

IHC (Immunohistochemistry)

(Anti-MDA5 antibody IHC of mouse kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

IHC (Immunohistochemistry)

(Anti-MDA5 antibody IHC of mouse small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

IHC (Immunohistochemistry)

(Anti-MDA5 antibody IHC of mouse pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Related Product Information for anti-IFIH1 antibody

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.

Product Categories/Family for anti-IFIH1 antibody

Family: DEAD box protein

NCBI and Uniprot Product Information

• NCBI GI #: 27886568
• NCBI GeneID: 64135
• NCBI Accession #: NP_071451.2
• NCBI GenBank Nucleotide #: NM_022168.3
• UniProt Accession #: Q9BYX4; Q2NKL6; Q6DC96; Q86X56; Q96MX8; Q9H3G6
• Molecular Weight: 25,129 Da
• NCBI Official Full Name: interferon-induced helicase C domain-containing protein 1
• NCBI Official Synonym Full Names: interferon induced with helicase C domain 1
• NCBI Official Symbol: IFIH1
• NCBI Official Synonym Symbols: AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19
• NCBI Protein Information: interferon-induced helicase C domain-containing protein 1; helicard; CADM-140 autoantigen; RIG-I-like receptor 2; helicase with 2 CARD domains; RNA helicase-DEAD box protein 116; murabutide down-regulated protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; melanoma differentiation associated protein-5; melanoma differentiation-associated protein 5; clinically amyopathic dermatomyositis autoantigen 140 kDa
• UniProt Protein Name: Interferon-induced helicase C domain-containing protein 1
• UniProt Gene Name: IFIH1
• UniProt Synonym Gene Names: MDA5; RH116; CADM-140 autoantigen; Helicard; MDA-5; RLR-2
• UniProt Entry Name: IFIH1_HUMAN