Rabbit anti-Human, Mouse Kynurenine 3-monooxygenase Polyclonal Antibody | anti-KMO antibody
Rabbit anti-human Kynurenine 3-monooxygenase polyclonal Antibody(KMO)
Gene Names
KMO; dJ317G22.1
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Kynurenine 3-monooxygenase, Antibody; Rabbit anti-human Kynurenine 3-monooxygenase polyclonal Antibody(KMO); Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase), KMO; anti-KMO antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid; PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Sequence Length
486
Applicable Applications for anti-KMO antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB:1:200-1000
IHC:1:20-1:200
IHC:1:20-1:200
Conjugate
Non-conjugated
Immunogen
Recombinant human Kynurenine 3-monooxygenase protein (1-260aa)
Immunogen Species
Homo sapiens (Human)
Research Area
Signal Transduction
Target Names
KMO
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using AAA18850 at dilution 1:100)
Related Product Information for anti-KMO antibody
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
kynurenine 3-monooxygenase
NCBI Official Synonym Full Names
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
NCBI Official Symbol
KMO
NCBI Official Synonym Symbols
dJ317G22.1
NCBI Protein Information
kynurenine 3-monooxygenase
UniProt Protein Name
Kynurenine 3-monooxygenase
UniProt Gene Name
KMO
UniProt Entry Name
KMO_HUMAN