WB (Western Blot)
Rabbit MOR1 Polyclonal Antibody | anti-MOR1 antibody
MOR1 Antibody
Gene Names
OPRM1; MOP; MOR; LMOR; MOR1; OPRM; M-OR-1
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
MOR1, Antibody; MOR1 Antibody; hMOP; LMOR; M-OR-1; MOP; MOR; MOR-1; Mu opiate receptor; Mu opioid receptor; Opioid receptor mu 1; OPRM; OPRM1 antibody; anti-MOR1 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Affinity Purified
Concentration
One hundred micrograms (100ug) of antibody in 180-200ul of antibody stabilization buffer. (varies by lot)
Sequence Length
493
Applicable Applications for anti-MOR1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:10,000
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500
Species Cross Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide taken within amino acid region 405-455 on human Mu-type opiod receptor isoform MOR-1i protein.
Expression
Expressed in brain. Isoform 16 and isoform 17 are detected in brain.
Molecular Function
G-protein coupled receptor, Receptor, Transducer
Structure
Forms homooligomers and heterooligomers with other GPCRs, such as OPRD1, OPRK1, OPRL1, NPFFR2, ADRA2A, SSTR2, CNR1 and CCR5 (probably in dimeric forms). Interacts with PPL; the interaction disrupts agonist-mediated G-protein activation. Interacts (via C-terminus) with DNAJB4 (via C-terminus). Interacts with calmodulin; the interaction inhibits the constitutive activity of OPRM1; it abolishes basal and attenuates agonist-stimulated G-protein coupling. Interacts with FLNA, PLD2, RANBP9 and WLS. Interacts with GPM6A, RTP4, SYP, GNAS, RGS9, RGS17, RGS20, RGS4, PPP1R9B and HINT1.
Subcellular Location
Cell membrane > Multi-pass membrane protein. Isoform 12: Cytoplasm
Preparation and Storage
Store at -20°C for long term storage
WB (Western Blot)
WB (Western Blot)
IHC (Immunohistochemistry)
IHC (Immunohistochemistry)
IHC (Immunohistochemistry)
IHC (Immunohistochemistry)
Related Product Information for anti-MOR1 antibody
Description: Affinity Purified Mu-type opioid receptor isoform MOR-1i Antibody
Overview: Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors.
Overview: Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors.
Product Categories/Family for anti-MOR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
mu-type opioid receptor isoform MOR-1i
NCBI Official Synonym Full Names
opioid receptor mu 1
NCBI Official Symbol
OPRM1
NCBI Official Synonym Symbols
MOP; MOR; LMOR; MOR1; OPRM; M-OR-1
NCBI Protein Information
mu-type opioid receptor
UniProt Protein Name
Mu-type opioid receptor
UniProt Gene Name
OPRM1
UniProt Synonym Gene Names
MOR1; M-OR-1; MOR-1; MOP; hMOP
UniProt Entry Name
OPRM_HUMAN
Similar Products
Product Notes
The MOR1 oprm1 (Catalog #AAA14412) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MOR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunohistochemistry: 1:100 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the MOR1 oprm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MOR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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