Rabbit PSAP Polyclonal Antibody | anti-PSAP antibody

(KO Validated) PSAP Polyclonal Antibody

Cat. Num. AAA22329

• Gene Names: PSAP; GLBA; SAP1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purification
• Synonyms: PSAP, Antibody; (KO Validated) PSAP Polyclonal Antibody; PSAP; GLBA; SAP1; prosaposin; anti-PSAP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.05% proclin300,50% glycerol,pH7.3.
• Concentration: 1mg/mL (varies by lot)

• Applicable Applications for anti-PSAP antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant fusion protein of human PSAP
• Research Area: Metabolism, Signal Transduction
• Preparation and Storage: Storage: -20 degree C/One year. Avoid freeze/thaw cycles.

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded mouse spleen using [KO Validated] PSAP Polyclonal Antibody at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.)

IHC (Immunohistchemistry)

(Immunohistochemistry of paraffin-embedded mouse kidney using [KO Validated] PSAP Polyclonal Antibody at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human tonsil using [KO Validated] PSAP Polyclonal Antibody at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human liver using [KO Validated] PSAP Polyclonal Antibody at dilution of 1:50 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.)

WB (Western Blot)

(Western blot analysis of extracts from wild type(WT) and PSAP Polyclonal Antibody knockout (KO) 293T cells using PSAP Polyclonal Antibody at 1:1000 dilution.)

WB (Western Blot)

(Western blot analysis of various lysates using PSAP Polyclonal Antibody antibody at 1:1000 dilution.)

WB (Western Blot)

(Western blot analysis of various lysates using PSAP Polyclonal Antibody at 1:1000 dilution.)

Related Product Information for anti-PSAP antibody

This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Product Categories/Family for anti-PSAP antibody

Antibodies; Primary Antibodies; Polyclonal Antibody

NCBI and Uniprot Product Information

• NCBI GI #: 110224476
• NCBI GeneID: 5660
• NCBI Accession #: NP_001035930.1
• NCBI GenBank Nucleotide #: NM_001042465.1
• UniProt Accession #: P07602; P07292; P15793; P78538; P78541; P78546; P78547; P78558; Q53Y86; Q6IBQ6; Q92739; Q92740
• Molecular Weight: 58,113 Da
• NCBI Official Full Name: proactivator polypeptide isoform b preproprotein
• NCBI Official Synonym Full Names: prosaposin
• NCBI Official Symbol: PSAP
• NCBI Official Synonym Symbols: GLBA; SAP1
• NCBI Protein Information: proactivator polypeptide; sphingolipid activator protein-1
• UniProt Protein Name: Proactivator polypeptide
• UniProt Gene Name: PSAP
• UniProt Synonym Gene Names: GLBA; SAP1; CSAct; SAP-1; SAP-2
• UniProt Entry Name: SAP_HUMAN