Rabbit anti-Human, Mouse ST2 Polyclonal Antibody | anti-Il1rl1 antibody

ST2 Antibody

Cat. Num. AAA10923

• Gene Names: Il1rl1; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: ST2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: ST2, Antibody; ST2 Antibody; ST2; T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1; Ste2; Interleukin-1 receptor-like 1; Lymphocyte antigen 84; interleukin 1 receptor-like 1; anti-Il1rl1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: ST2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid; T2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 567

• Applicable Applications for anti-Il1rl1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guidline for product use.
• Conjugate: Unconjugated
• Immunogen: ST2 antibody was raised against a synthetic peptide corresponding to 16 amino acids at the amino-terminus of mouse ST2.; This peptide is common to all three known ST2 isoforms.; The immunogen is located within amino acids 40-90 of ST2.
• Homology: Predicted species reactivity based in immunogen sequence: Rat (88%)
• Preparation and Storage: ST2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of ST2 in human lung cancer tissue with ST2 antibody at 5 μg/ml.Green: ST2 Antibody (3363)Blue: DAPI staining)

IHC (Immunohistochemistry)

(Immunohistochemistry of ST2 in human lung cancer tissue with ST2 antibody at 5 μg/ml.)

IHC (Immunohistochemistry)

(Immunohistochemistry of ST2 in mouse kidney tissue with ST2 antibody at 2 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of ST2 in Mouse Kidney cells with ST2 antibody at 20 μg/mL.)

IHC (Immunohistochemistry)

(Immunohistochemistry of ST2 in human liver tissue with ST2 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of ST2 in 293 cell lysate with ST2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-Il1rl1 antibody

ST2 Antibody: ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.

NCBI and Uniprot Product Information

• NCBI GI #: 286101
• NCBI GeneID: 17082
• UniProt Accession #: P14719; Q05208
• NCBI Official Full Name: ST2L protein
• NCBI Official Synonym Full Names: interleukin 1 receptor-like 1
• NCBI Official Symbol: Il1rl1
• NCBI Official Synonym Symbols: T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1
• NCBI Protein Information: interleukin-1 receptor-like 1; lymphocyte antigen 84
• UniProt Protein Name: Interleukin-1 receptor-like 1
• UniProt Gene Name: Il1rl1
• UniProt Synonym Gene Names: Ly84; St2; Ste2
• UniProt Entry Name: ILRL1_MOUSE