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Osteoprotegerin (OPG) Recombinant Protein | OPG recombinant protein

Recombinant Human Osteoprotegerin, His (OPG Human)

Gene Names
TNFRSF11B; OPG; TR1; OCIF; PDB5
Reactivity
Human
Applications
Western Blot
Purity
Greater than 80.0% as determined by:
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-Page.
Synonyms
Osteoprotegerin (OPG); N/A; Recombinant Human Osteoprotegerin, His (OPG Human); OPG recombinant protein
Ordering
Host
E.Coli
Reactivity
Human
Purity/Purification
Greater than 80.0% as determined by:
(a)Analysis by RP-HPLC.
(b)Analysis by SDS-Page.
Form/Format
The protein was lyophilized from concentrated (1mg/ml) solution with 1X PBS, 0.1% SDS and 1mM DTT.
Sequence Length
401
Applicable Applications for OPG recombinant protein
WB (Western Blot)
Reconstitution
It is recommended to reconstitute the lyophilized Osteoprotegerin in sterile water not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Preparation and Storage
Lyophilized Osteoprotegerin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Osteoprotegerin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Related Product Information for OPG recombinant protein
Recombinant Human OCIF produced E.coli cells is a single, non-glycosylated, polypeptide chain containing amino acids 201-401 and having a molecular mass of 31 kDa which includes 4 kDa His tag. The OPG is purified by chromatographic techniques.
References
1. Effects of hypolipemic drugs on the osteoprotegerin - sRANKL system in patients with coronary artery disease. Thromb Haemost 2007 May;97(5):868-702. Plasma osteoprotegerin levels in the general population: relation to indices of left ventricular structure and function. Hypertension 2007 Jun;49(6):1392-83. The sex-specific association of serum osteoprotegerin and receptor activator of nu clear factor kappaB legend with bone mineral density in older adults: the Rancho Bernardo study. Eur J Endocrinol 2007 May;156(5):555-624. Thyroid hormone deficiency and postmenopausal status independently increase serum osteoprotegerin concentrations in women. Eur J Endocrinol 2007 May;156(5):539-455. Abnormal bone remodeling process is due to an imbalance in the receptor activator of nuclear factor-kappaB ligand (RANKL)/osteoprotegerin (OPG) axis in patients with solid tumors metastatic to the skeleton.Acta Oncol 2007;46(2):221-96. Inhibition of tooth movement by osteoprotegerin vs. pamidronate under conditions of constant orthodontic force. Eur J Oral Sci 2007 Apr;115(2):131-6

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
osteoprotegerin
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily member 11b
NCBI Official Symbol
TNFRSF11B
NCBI Official Synonym Symbols
OPG; TR1; OCIF; PDB5
NCBI Protein Information
tumor necrosis factor receptor superfamily member 11B
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 11B
UniProt Gene Name
TNFRSF11B
UniProt Synonym Gene Names
OCIF; OPG
UniProt Entry Name
TR11B_HUMAN

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Product Notes

The OPG tnfrsf11b (Catalog #AAA76542) is a Recombinant Protein produced from E.Coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human Osteoprotegerin, His (OPG Human) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Osteoprotegerin (OPG) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the OPG tnfrsf11b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Osteoprotegerin (OPG), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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