Peroxiredoxin-1 Active Protein | PRDX1 active protein

Recombinant Human Peroxiredoxin-1

Cat. Num. AAA10855

• Gene Names: PRDX1; PAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Synonyms: Peroxiredoxin-1; N/A; Recombinant Human Peroxiredoxin-1; PRDX1 Human; Peroxiredoxin-1 Human Recombinant; EC 1.11.1.15; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Proliferation-associated gene protein; Natural killer cell-enhancing factor A; NKEF-A; PRDX1; TDPX2; PRDX-1; PAG; PAGA; PRX1; PAGB; PRXI; MSP23; NKEFA; PRDX1 active protein

• Host: E Coli
• Purity/Purification: Greater than 90.0% as determined by SDS-PAGE.
• Form/Format: The Peroxiredoxin solution (1mg/ml)contains 20mM Tris-HCl pH-7.5, & 20% glycerol.; Sterile Filtered colorless solution.
• Sequence: MGSSHHHHHH SSGLVPRGSHMSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVQK SKEYFSKQK
• Sequence Length: 199

• Biological Activity: Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25 degree C for minute. Specific activity is >2,000pmol/min/ug.
• Preparation and Storage: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.; For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).; Avoid multiple freeze-thaw cycles.

Related Product Information for PRDX1 active protein

Description: Peroxiredoxin Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain (1-199) containing 219 amino acids and having a molecular mass of 24 kDa. The Peroxiredoxin is purified by proprietary chromatographic techniques.

Introduction: PRDX1 is part of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. PRDX1 is an important protector of red blood cells against reactive oxygen species and in tumor prevention.PRDX1 is antioxidant protective in cells, and contributes to the antiviral activity of CD8(+) T-cells. PRDX1 has a proliferative effect and is involved in cancer development or progression.Peroxiredoxin-1 is plays a role in redox regulation of the cell. Peroxiredoxin decreases peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. Peroxiredoxin is involved in eliminating peroxides generated during metabolism. Peroxiredoxin participates in the signaling cascades of growth factors and TNF-alpha by regulating the intracellular concentrations of h(2)o(2).

Product Categories/Family for PRDX1 active protein

Enzymes; Peroxiredoxin

NCBI and Uniprot Product Information

• NCBI GI #: 320461711
• NCBI GeneID: 5052
• NCBI Accession #: NP_001189360.1
• NCBI GenBank Nucleotide #: NM_001202431.1
• UniProt Accession #: Q06830; P35703; Q2V576; Q5T154; Q5T155; B5BU26; D3DPZ8
• NCBI Official Full Name: peroxiredoxin-1
• NCBI Official Synonym Full Names: peroxiredoxin 1
• NCBI Official Symbol: PRDX1
• NCBI Official Synonym Symbols: PAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A
• NCBI Protein Information: peroxiredoxin-1; natural killer cell-enhancing factor A; natural killer-enhancing factor A; proliferation-associated gene A; proliferation-associated gene protein; thioredoxin peroxidase 2; thioredoxin-dependent peroxide reductase 2
• UniProt Protein Name: Peroxiredoxin-1
• UniProt Gene Name: PRDX1
• UniProt Synonym Gene Names: PAGA; PAGB; TDPX2; NKEF-A; PAG
• UniProt Entry Name: PRDX1_HUMAN