Rabbit anti-Human ABCA7 Polyclonal Antibody | anti-ABCA7 antibody

ABCA7 Antibody

Cat. Num. AAA10915

• Gene Names: ABCA7; ABCX; ABCA-SSN
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunocytochemistry, Immunofluorescence
• Purity: ABCA7 Antibody is affinity chromatography purified via peptide column.
• Synonyms: ABCA7, Antibody; ABCA7 Antibody; ABCX; ABCA-SSN; ATP-binding cassette sub-family A member 7; ATP-binding cassette, sub-family A (ABC1), member 7; anti-ABCA7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ABCA7 antibody is human specific. At least two alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Purity/Purification: ABCA7 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 2146

• Applicable Applications for anti-ABCA7 antibody: ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
• Application Notes: ABCA7 antibody can be used for detection of ABCA7 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 5 mug/mL. For immunofluorescence start at 5 mug/mL.
• Conjugate: Unconjugated
• Immunogen: ABCA7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ABCA7.
• Buffer: ABCA7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: ABCA7 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of ABCA7 in human spleen tissue with ABCA7 antibody at 20 μg/ml.Red: ABCA7 Antibody (6889)Blue: DAPI staining)

IHC (Immunohistochemistry)

(Immunohistochemistry of ABCA7 in human spleen tissue with ABCA7 antibody at 5μg/ml.)

ICC (Immunocytochemistry)

(Immunocytochemistry of ABCA7 in 293 cells with ABCA7 antibody at 5 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of ABCA7 in 293 cells with ABCA7 antibody at 20 μg/mL.)

IHC (Immunohistochemistry)

(Immunohistochemistry of ABCA7 in human spleen tissue with ABCA7 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of ABCA7 in 293 cell lysate with ABCA7 antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-ABCA7 antibody

ABCA7 Antibody: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.

NCBI and Uniprot Product Information

• NCBI GI #: 150417984
• NCBI GeneID: 10347
• NCBI Accession #: NP_061985
• NCBI GenBank Nucleotide #: NM_019112.3
• UniProt Accession #: Q8IZY2; Q96S58; Q9BZC4; Q9NR73; Q9UKP8
• Molecular Weight: 218,497 Da
• NCBI Official Full Name: ATP-binding cassette sub-family A member 7
• NCBI Official Synonym Full Names: ATP-binding cassette, sub-family A (ABC1), member 7
• NCBI Official Symbol: ABCA7
• NCBI Official Synonym Symbols: ABCX; ABCA-SSN
• NCBI Protein Information: ATP-binding cassette sub-family A member 7; autoantigen SS-N; macrophage ABC transporter
• UniProt Protein Name: ATP-binding cassette sub-family A member 7
• UniProt Gene Name: ABCA7
• UniProt Entry Name: ABCA7_HUMAN