Rat anti-Mouse CD44 Monoclonal Antibody | anti-CD44 antibody

Anti-Mouse CD44, Purified (Clone KM81) (rat IgG2a)

Cat. Num. AAA14269

• Gene Names: CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III
• Reactivity: Mouse
• Applications: Immunohistochemistry, Flow Cytometry
• Synonyms: CD44, Antibody; Anti-Mouse CD44, Purified (Clone KM81) (rat IgG2a); CD44, Purified (Clone KM81) (rat IgG2a); Anti-Mouse CD44 Monoclonal Antibody; anti-CD44 antibody

• Host: Rat
• Reactivity: Mouse
• Clonality: Monoclonal
• Isotype: Rat IgG2a
• Clone Number: KM81
• Specificity: CD44 (Ly 24, Pgp-1) (Mouse CD44)
• Form/Format: Purified
• Sequence Length: 43

• Applicable Applications for anti-CD44 antibody: Immunohistochemistry (IHC), Flow Cytometry (FC)
• Hybridoma Production: Immunization: Immunogen: Bone Marrow Derived Stromal Cells (clone BMS2); Donor: Lou/MN Rat; Fusion Partner: SP 2/0
• Presentation: Purified IgG buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography). For maximum recovery of contents, spin down tube before use.
• Preparation and Storage: For all formats, store at 4 degree C. DO NOT FREEZE APC and PE conjugates. For long term storage (Purified, Biotin, FITC, No Azide), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.

Application Data

(ATH mouse bone marrow stained with anti-CD44 (clone: KM81) (filled histogram) or Rat IgG2a isotype control (open histogram).N.B. Appropriate control samples should always be included in any labelling studies. * For optimal results in various applications, it is recommended that each investigator determine dilutions appropriate for individual use.)

Related Product Information for anti-CD44 antibody

anti-mouse CD44 (Pgp-1, Ly-24) monoclonal antibody recognizes a 95 kDa glycoprotein found on most hematopoietic cells. It is thought to be important in the regulation of migratory properties of lymphocytes during development and the regulation of the interaction with bone marrow stromal cells during hematopoiesis. CD44 functions as a receptor for hyaluronate, although some cells expressing CD44 do not bind hyaluronate. This antibody has been shown to inhibit the growth of lymphoid and myeloid cells in long term bone marrow cultures. It also blocks the adhesive interactions of B cell hybridomas to a cloned stromal line or to hyaluronate coated dishes.

NCBI and Uniprot Product Information

• NCBI GI #: 685122
• NCBI GeneID: 960
• UniProt Accession #: P16070; O95370; P22511; Q04858; Q13419; Q13957; Q13958; Q13959; A5YRN9; B6EAT9; D3DR12; D3DR13
• Molecular Weight: 81,538 Da
• NCBI Official Full Name: CD44
• NCBI Official Synonym Full Names: CD44 molecule (Indian blood group)
• NCBI Official Symbol: CD44
• NCBI Official Synonym Symbols: IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III
• NCBI Protein Information: CD44 antigen; epican; Hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; heparan sulfate proteoglycan; cell surface glycoprotein CD44; extracellular matrix receptor III; chondroitin sulfate proteoglycan 8; GP90 lymphocyte homing/adhesion receptor; hematopoietic cell E- and L-selectin ligand; homing function and Indian blood group system
• UniProt Protein Name: CD44 antigen
• UniProt Gene Name: CD44
• UniProt Synonym Gene Names: LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I
• UniProt Entry Name: CD44_HUMAN