Alpha-hemolysin Recombinant Protein | hly recombinant protein
Recombinant Staphylococcus aureus Alpha-hemolysin (hly)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Alpha-hemolysin; N/A; Recombinant Staphylococcus aureus Alpha-hemolysin (hly); Alpha-toxin; hly recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
27-319aa; Full Length of Mature Protein
Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
Related Product Information for hly recombinant protein
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity.
References
Synthetic effects of secG and secY2 mutations on exoproteome biogenesis in Staphylococcus aureus.Sibbald M.J., Winter T., van der Kooi-Pol M.M., Buist G., Tsompanidou E., Bosma T., Schafer T., Ohlsen K., Hecker M., Antelmann H., Engelmann S., van Dijl J.M.J. Bacteriol. 192:3788-3800(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35.3 kDa
NCBI Official Full Name
alpha-hemolysin
NCBI Official Symbol
SAOUHSC_01121
NCBI Protein Information
alpha-hemolysin
UniProt Protein Name
Alpha-hemolysin
UniProt Gene Name
hly
UniProt Synonym Gene Names
hla; Alpha-HL
UniProt Entry Name
HLA_STAA8
