Rabbit anti-Human IL-1F8 Polyclonal Antibody | anti-IL-1F8 antibody

IL-1F8 Polyclonal Antibody

Cat. Num. AAA29281

• Gene Names: IL36B; FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA)
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Synonyms: IL-1F8; Polyclonal Antibody; IL-1F8 Polyclonal Antibody; IL36B; IL1F8; IL1H2; Interleukin-36 beta; FIL1 eta; Interleukin-1 eta; IL-1 eta; Interleukin-1 family member 8; Interleukin-1 homolog 2; IL-1H2; anti-IL-1F8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal

• Applicable Applications for anti-IL-1F8 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohistchemistry)

(Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.)

IHC (Immunohistochemistry)

(Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.)

WB (Western Blot)

(Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.)

IHC (Immunohistochemistry-Paraffin)

(Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.)

IHC (Immunohistochemistry-Paraffin)

(Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.)

WB (Western Blot)

(Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.)

Related Product Information for anti-IL-1F8 antibody

Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1, and the production of proinflammatory cytokines such as TNF-alpha, IL- 8 and IL-6.

NCBI and Uniprot Product Information

• NCBI GI #: 20070252
• NCBI GeneID: 27177
• NCBI Accession #: NP_055253.2
• NCBI GenBank Nucleotide #: NM_014438.4
• UniProt Accession #: Q9NZH7; Q3MIH0; Q53SR6; Q7RTZ7; Q9UHA5
• Molecular Weight: 18,522 Da
• NCBI Official Full Name: interleukin-36 beta isoform 1
• NCBI Official Synonym Full Names: interleukin 36, beta
• NCBI Official Symbol: IL36B
• NCBI Official Synonym Symbols: FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA)
• NCBI Protein Information: interleukin-36 beta; FIL1 eta; IL-1 eta; IL-1F8 (FIL1-eta); interleukin-1 eta; interleukin 1, eta; interleukin-1 homolog 2; Interleukin-1 Superfamily e; family of interleukin 1-eta; interleukin-1 family member 8; IL1F8 (Canonical product IL-1F8a); interle
• UniProt Protein Name: Interleukin-36 beta
• UniProt Gene Name: IL36B
• UniProt Synonym Gene Names: IL1F8; IL1H2; IL-1 eta; IL-1F8; IL-1H2
• UniProt Entry Name: IL36B_HUMAN