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IHC (Immunohistochemistry)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
Rabbit anti-Human CLECSF6 Polyclonal Antibody | anti-CLECSF6 antibody
CLECSF6 Polyclonal Antibody
Gene Names
CLEC4A; DCIR; LLIR; DDB27; CLECSF6; HDCGC13P
Reactivity
Human
Applications
Western Blot
Synonyms
CLECSF6; Polyclonal Antibody; CLECSF6 Polyclonal Antibody; C-type lectin domain family 4 member A (C-type lectin DDB27)(C-type lectin superfamily member 6)(Dendritic cell immunoreceptor)(Lectin-like immunoreceptor); anti-CLECSF6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Applicable Applications for anti-CLECSF6 antibody
Western Blot (WB)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemistry)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
WB (Western Blot)
(Dilution: WB 1:500-2000, ELISA 1:10000-20000)
Related Product Information for anti-CLECSF6 antibody
C-type lectin receptor that binds carbohydrates mannose and fucose but also weakly interacts with N-acetylglucosamine (GlcNAc) in a Ca (2+)-dependent manner (PubMed:10438934). Once triggered by antigen, it is internalized by clathrin-dependent endocytosis and delivers its antigenic cargo into the antigen presentation pathway resulting in cross-priming of CD8 (+) T cells. This cross-presentation and cross-priming are enhanced by TLR7 and TLR8 agonists with increased expansion of the CD8 (+) T cells, high production of IFNG and TNF with reduced levels of IL4, IL5 and IL13 (PubMed:20530286). In plasmacytoid dendritic cells, inhibits TLR9-mediated IFNA and TNF production (PubMed:18258799). May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation (PubMed:10438934).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
237
NCBI Official Full Name
C-type lectin domain family 4 member A
NCBI Official Synonym Full Names
C-type lectin domain family 4, member A
NCBI Official Symbol
CLEC4A
NCBI Official Synonym Symbols
DCIR; LLIR; DDB27; CLECSF6; HDCGC13P
NCBI Protein Information
C-type lectin domain family 4 member A; C-type lectin DDB27; lectin-like immunoreceptor; dendritic cell immunoreceptor; C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6
UniProt Protein Name
C-type lectin domain family 4 member A
UniProt Gene Name
CLEC4A
UniProt Synonym Gene Names
CLECSF6; DCIR; LLIR
UniProt Entry Name
CLC4A_HUMAN
Similar Products
Product Notes
The CLECSF6 clec4a (Catalog #AAA29339) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLECSF6 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLECSF6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CLECSF6 clec4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLECSF6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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