Application Data
(Image: Western blot analysis of ACAN in L929 whole cell extracts.)
Aggrecan Neoepitope Antibody | anti-ACAN antibody
Aggrecan Neoepitope, Affinity Purified Antibody, Rabbit
Gene Names
ACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP
Reactivity
Cow, Cat, Human, Mouse, Porcine, Rat
Applications
Western Blot, Immunofluorescence
Synonyms
Aggrecan Neoepitope; N/A; Aggrecan Neoepitope, Affinity Purified Antibody, Rabbit; anti-ACAN antibody
Reactivity
Cow, Cat, Human, Mouse, Porcine, Rat
Form/Format
Liquid; PBS, 30% glycerol with 0.1% Sodium Azide as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
721
Applicable Applications for anti-ACAN antibody
WB (Western Blot), IF (Immunofluorescence)
Type Info
Rabbit IgG
Immunogen
Synthetic peptide corresponding to residues C G G N(a.a. 387) I T E G E(a.a. 392) of human aggrecan.
Preparation and Storage
Store frozen. Aliquot as undiluted antisera and immediately place at -20°C. Antisera may havebecome trapped in top of vial during shipping. Centrifugation of vial is recommended before opening.
Stable for up to 6 months at -20°C. Avoid repeated freeze/thaw cycles.
Stable for up to 6 months at -20°C. Avoid repeated freeze/thaw cycles.
Application Data
(Image: Western blot analysis of ACAN in L929 whole cell extracts.)
Application Data
(Image: Western blot analysis of ACAN in L929 whole cell extracts.)
Application Data
(This ACAN antibodyis useful for immunofluorescence and W estern blot. In W B a band is detected at ~61 kDa representing the neoepitope sequence (NITEGE) generated by aggrecanase-mediated cleavage at Glu373-Ala374 of aggrecan core proteins.)
Application Data
(This ACAN antibodyis useful for immunofluorescence and W estern blot. In W B a band is detected at ~61 kDa representing the neoepitope sequence (NITEGE) generated by aggrecanase-mediated cleavage at Glu373-Ala374 of aggrecan core proteins.)
Related Product Information for anti-ACAN antibody
Aggrecan is a member of large, aggregating proteoglycans (also including, versican, brevican and neurocan) found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase (ADAMTS).
Product Categories/Family for anti-ACAN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Aggrecan
NCBI Official Synonym Full Names
aggrecan
NCBI Official Symbol
ACAN
NCBI Official Synonym Symbols
AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP
NCBI Protein Information
aggrecan core protein
UniProt Protein Name
Aggrecan core protein
UniProt Gene Name
ACAN
UniProt Synonym Gene Names
AGC1; CSPG1; MSK16; CSPCP; Chondroitin sulfate proteoglycan 1
UniProt Entry Name
PGCA_HUMAN
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Product Notes
The ACAN acan (Catalog #AAA76451) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Aggrecan Neoepitope, Affinity Purified Antibody, Rabbit reacts with Cow, Cat, Human, Mouse, Porcine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Aggrecan Neoepitope can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence). Researchers should empirically determine the suitability of the ACAN acan for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aggrecan Neoepitope, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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