Actin, cytoplasmic 1 protein Recombinant Protein | ACTB recombinant protein

Recombinant Human Actin, cytoplasmic 1 protein

Cat. Num. AAA116203

• Gene Names: ACTB; BRWS1; PS1TP5BP1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Actin, cytoplasmic 1 protein; N/A; Recombinant Human Actin, cytoplasmic 1 protein; Beta-actin; ACTB recombinant protein

• Host: E Coli
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Liquid containing glycerol
• Sequence Positions: 102-375aa; Partial
• Sequence: PVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF

• Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our or email to for more details.
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for ACTB recombinant protein

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Product Categories/Family for ACTB recombinant protein

Signal Transduction

References

Evolutionary conservation in the untranslated regions of actin mRNAs DNA sequence of a human beta-actin cDNA.Ponte P., Ng S.Y., Engel J., Gunning P., Kedes L.Nucleic Acids Res. 12:1687-1696(1984) Molecular structure of the human cytoplasmic beta-actin gene interspecies homology of sequences in the introns.Nakajima-Iijima S., Hamada H., Reddy P., Kakunaga T.Proc. Natl. Acad. Sci. U.S.A. 82:6133-6137(1985) Direct proof that the primary site of action of cytochalasin on cell motility processes is actin.Ohmori H., Toyama S., Toyama S.J. Cell Biol. 116:933-941(1992) NIEHS SNPs programThe DNA sequence of human chromosome 7.Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.Nature 424:157-164(2003) Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.Nat. Biotechnol. 21:566-569(2003) Bienvenut W.V.Submitted (JUN-2005) to UniProtKB Lubec G., Afjehi-Sadat L., Chen W.-Q., Sun Y.Submitted (DEC-2008) to UniProtKB Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions.Hanukoglu I., Tanese N., Fuchs E.J. Mol. Biol. 163:673-678(1983) Exportin 6 a novel nuclear export receptor that is specific for profilin.actin complexes.Stueven T., Hartmann E., Goerlich D.EMBO J. 22:5928-5940(2003) Emerin caps the pointed end of actin filaments evidence for an actin cortical network at the nuclear inner membrane.Holaska J.M., Kowalski A.K., Wilson K.L.PLoS Biol. 2:1354-1362(2004) Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.Giannakopoulos N.V., Luo J.K., Papov V., Zou W., Lenschow D.J., Jacobs B.S., Borden E.C., Li J., Virgin H.W., Zhang D.E.Biochem. Biophys. Res. Commun. 336:496-506(2005) HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration.Lu X., Chen J., Malumbres R., Cubedo Gil E., Helfman D.M., Lossos I.S.Blood 110:4268-4277(2007) Molecular composition of IMP1 ribonucleoprotein granules.Joeson L., Vikesaa J., Krogh A., Nielsen L.K., Hansen T., Borup R., Johnsen A.H., Christiansen J., Nielsen F.C.Mol. Cell. Proteomics 6:798-811(2007) Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.Lange M., Kaynak B., Forster U.B., Toenjes M., Fischer J.J., Grimm C., Schlesinger J., Just S., Dunkel I., Krueger T., Mebus S., Lehrach H., Lurz R., Gobom J., Rottbauer W., Abdelilah-Seyfried S., Sperling S.Genes Dev. 22:2370-2384(2008) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.Anal. Chem. 81:4493-4501(2009) Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes.Li L.Y., Chen H., Hsieh Y.H., Wang Y.N., Chu H.J., Chen Y.H., Chen H.Y., Chien P.J., Ma H.T., Tsai H.C., Lai C.C., Sher Y.P., Lien H.C., Tsai C.H., Hung M.C.Cancer Res. 71:4269-4279(2011) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.Procaccio V., Salazar G., Ono S., Styers M.L., Gearing M., Davila A., Jimenez R., Juncos J., Gutekunst C.-A., Meroni G., Fontanella B., Sontag E., Sontag J.-M., Faundez V., Wainer B.H.Am. J. Hum. Genet. 78:947-960(2006) GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.Fujiki R., Chikanishi T., Hashiba W., Ito H., Takada I., Roeder R.G., Kitagawa H., Kato S.Nature 459:455-459(2009) ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.Li M.M., Nilsen A., Shi Y., Fusser M., Ding Y.H., Fu Y., Liu B., Niu Y., Wu Y.S., Huang C.M., Olofsson M., Jin K.X., Lv Y., Xu X.Z., He C., Dong M.Q., Rendtlew Danielsen J.M., Klungland A., Yang Y.G.Nat. Commun. 4:1832-1832(2013) De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.Riviere J.B., van Bon B.W., Hoischen A., Kholmanskikh S.S., O'Roak B.J., Gilissen C., Gijsen S., Sullivan C.T., Christian S.L., Abdul-Rahman O.A., Atkin J.F., Chassaing N., Drouin-Garraud V., Fry A.E., Fryns J.P., Gripp K.W., Kempers M., Kleefstra T., Mancini G.M., Nowaczyk M.J., van Ravenswaaij-Arts C.M., Roscioli T., Marble M., Rosenfeld J.A., Siu V.M., de Vries B.B., Shendure J., Verloes A., Veltman J.A., Brunner H.G., Ross M.E., Pilz D.T., Dobyns W.B.Nat. Genet. 44:440-444(2012)

NCBI and Uniprot Product Information

• NCBI GI #: 4501885
• NCBI GeneID: 60
• NCBI Accession #: NP_001092.1
• NCBI GenBank Nucleotide #: NM_001101.3
• UniProt Accession #: P60709; P02570; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5
• Molecular Weight: 34.6 kDa
• NCBI Official Full Name: actin, cytoplasmic 1
• NCBI Official Synonym Full Names: actin, beta
• NCBI Official Symbol: ACTB
• NCBI Official Synonym Symbols: BRWS1; PS1TP5BP1
• NCBI Protein Information: actin, cytoplasmic 1
• UniProt Protein Name: Actin, cytoplasmic 1
• UniProt Gene Name: ACTB
• UniProt Entry Name: ACTB_HUMAN