Application Data
PLTX-II Active Peptide
PLTX-II
Synonyms
PLTX-II; N/A; PLTX-II active peptide
Form/Format
This vial contains exactly 0.10 mg (20 nmol ) of the titled compound, which has been lyophilized as an amorphous powder from aqueous solution.
Apprearance: White amorphous powder
Apprearance: White amorphous powder
Sequence
Ala-Asp-Cys-Ser-Ala-Thr-Gly-Asp-Thr-CysAsp- His-Thr-Lys-Lys-cys-cys-Asp-Asp-CysTyr- Thr-cys-Arg-Cys-Gly-Thr-Pro-Trp-GlyAla- Asn-Cys-Arg-Cys-Asp-Tyr-Tyr-Lys-AlaArg- Cys-Asp-Thr(Palmitoyl)-NHc
(Disulfide bonds undetermined)
(M.W.5108.73) C203H313N61O70S10
(Disulfide bonds undetermined)
(M.W.5108.73) C203H313N61O70S10
Solution
Do not remove the cap. Inject 200 ul of 0.1% acetic acid solution into the vial using a calibrated syringe. Dissolve all the contents thoroughly. This procedure furnishes a 0.1 mM solution of the titled compound.
Specific Optical Rotation
[Alpha]^20D -5.5 * (c 0.26, H2O)
Amino Acid Analysis
Acid Hydolysis: 6N HCl. 110 degree C, 22h *with thioglycolic acid
Asp (8) 8.04 Thr (6) 5.73 Ser (1) 0.95 Pro (1) 1.03
Gly (3) 3.00 Ala (4) 3.90 1/2 Cystine (10) 9.66 Tyr (3)2.98
His (1)0.99 Lys (3)3.00 NH3 (2) 3.18 Trp(100.62*
Arg (3) 2.96
Asp (8) 8.04 Thr (6) 5.73 Ser (1) 0.95 Pro (1) 1.03
Gly (3) 3.00 Ala (4) 3.90 1/2 Cystine (10) 9.66 Tyr (3)2.98
His (1)0.99 Lys (3)3.00 NH3 (2) 3.18 Trp(100.62*
Arg (3) 2.96
Thin Layer Chromatography
Single spot
Cellulose Layer
Application: 50ug
Solvent system: n-BuOH:AcOH:H2O:pyridine=15:3:12:10
Located by ninhydrin and Pauly reagent
Solvent system: n-BuOH:AcOH:H2O:pyridine=15:3:12:10
Located by ninhydrin and Pauly reagent
Preparation and Storage
Storage (Solution): After preparing 100-200 ul aliquots, freeze them at -20 degree C or below until use. TIle aqueous solution should be used within a few weeks.
Storage (powder): TIle undissolved peptide is stable at -2C degree C for more than one year.
Storage (powder): TIle undissolved peptide is stable at -2C degree C for more than one year.
Application Data
Application Data
Related Product Information for PLTX-II active peptide
(Spider, Plectreurys tristes) Ala-Asp-Cys-Ser-Ala-Thr-Gly-Asp-Thr-Cys-Asp-His-Thr-Lys-Lys-Cys-Cys-Asp-Asp-Cys-Tyr-Thr-Cys-Arg-Cys-Gly-Thr-Pro-Trp-Gly-Ala-Asn-Cys-Arg-Cys-Asp-Tyr-Tyr-Lys-Ala-Arg-Cys-Asp-Thr(Palmitoyl)-NH2 (Disulfide bonds undetermined) (M.W. 5108.7) C208H313N61O70S10 Presynaptic Ca2+ Channel Blocker W.D. Branton, L. Kolton, Y.N. Jan, and L.Y. Jan, J. Neurosci., 7, 4195 (1987). (Original) H.-T. Leung, W.D. Branton, H.S. Phillips, L. Jan, and L. Byerly, Neuron, 3, 767 (1989). (Pharmacol.) W.D. Branton, M.S. Rudnick, Y. Zhou, E.D. Eccleston, G.B. Fields, and L.D. Bowers, Nature, 365, 496 (1993). (Thr(Pal)amide) J. Bódi, H. Nishio, Y. Zhou, W.D. Branton, T. Kimura, and S. Sakakibara, Pept. Res., 8, 228 (1995). (Chem. Synthesis & Biological Activity)
Product Categories/Family for PLTX-II active peptide
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Product Notes
The PLTX-II (Catalog #AAA60593) is an Active Peptide and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Ala-Asp-Cy s-Ser-Ala- Thr-Gly-As p-Thr-CysA sp- His-Thr-Ly s-Lys-cys- cys-Asp-As p-CysTyr- Thr-cys-Ar g-Cys-Gly- Thr-Pro-Tr p-GlyAla- Asn-Cys-Ar g-Cys-Asp- Tyr-Tyr-Ly s-AlaArg- Cys-Asp-Th r(Palmitoy l)-NHc (Disulfide bonds undetermin ed) (M. W.5108.73) C203H313N6 1O70S10. It is sometimes possible for the material contained within the vial of "PLTX-II, Active Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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