Standard Curve (Sample)
Human ALK1 ELISA Kit | ACVRL1 elisa kit
Human ALK1 ELISA Kit
Gene Names
ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
Reactivity
Human
Synonyms
ALK1; N/A; Human ALK1 ELISA Kit; ACVRLK1; Serine/threonine-protein kinase receptor R3; SKR3; Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I; ACVRL1 elisa kit
Reactivity
Human
Specificity
The Human ALK1 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human ALK1 proteins within the range of 46.9 pg/ml - 3000 pg/ml.
Sequence Length
503
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<15 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for ACVRL1 elisa kit
Principle of the Assay: The Human ALK1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human ALK1 in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Human ALK1 coated on a 96-well plate. Standards and samples are pipetted into the wells and ALK1 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human ALK1 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of ALK1 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene. It is also known as activin receptor-like kinase 1, or ALK1. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Background: Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene. It is also known as activin receptor-like kinase 1, or ALK1. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,124 Da
NCBI Official Full Name
serine/threonine-protein kinase receptor R3
NCBI Official Synonym Full Names
activin A receptor like type 1
NCBI Official Symbol
ACVRL1
NCBI Official Synonym Symbols
HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
NCBI Protein Information
serine/threonine-protein kinase receptor R3
UniProt Protein Name
Serine/threonine-protein kinase receptor R3
UniProt Gene Name
ACVRL1
UniProt Synonym Gene Names
ACVRLK1; ALK1; SKR3; ALK-1; TSR-I
UniProt Entry Name
ACVL1_HUMAN
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Product Notes
The Human ACVRL1 acvrl1 (Catalog #AAA263013) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA263013 ELISA Kit recognizes Human ACVRL1. It is sometimes possible for the material contained within the vial of "ALK1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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