Allograft Inflammatory Factor 1 Recombinant Protein | AIF1 recombinant protein

Recombinant Human Allograft Inflammatory Factor 1

Cat. Num. AAA38736

• Gene Names: AIF1; IBA1; IRT1; AIF-1; IRT-1
• Purity: Greater than 90% as determined by SDS PAGE.
• Synonyms: Allograft Inflammatory Factor 1; N/A; Recombinant Human Allograft Inflammatory Factor 1; AIF1 Human; Allograft Inflammatory Factor 1 Human Recombinant; AIF-1; Allograft inflammatory factor 1; Em:AF129756.17; G1; IBA1; Ionized calcium-binding adapter molecule 1; IRT-1; Protein G1; AIF1; AIF1 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 90% as determined by SDS PAGE.
• Form/Format: Filtered and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl pH-7.5.; Filtered White lyophilized (freeze-dried) powder.
• Sequence: MKHHHHHHASQTRDLQGGKAF­GLLKAQQEERLDE­INKQFLDDPKYSSDED­LPSKLEGFKEKYMEF­DLNGNGDIDIMSLKRMLEK­LGVPKTHLELKKLI­GEVSSGSGETFSYP­DFLRMMLGKRSAIL­KMILMYEEKAREKEK­PTGPPAKKAISELP
• Sequence Length: 147

• Solubility: Add 0.2 ml of deionized water and let the lyophilized pellet dissolve completely.
• Preparation and Storage: For long term, store lyophilized AIF1 at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.The lyophilized protein remains stable for 24 months when stored at -20 degree C.

Related Product Information for AIF1 recombinant protein

Description: The AIF1 Human Recombinant contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal His tag.

Introduction: Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor malignancy in humans.

Product Categories/Family for AIF1 recombinant protein

Cytokines and Growth Factors; Cytokines

NCBI and Uniprot Product Information

• NCBI GI #: 14574568
• NCBI GeneID: 199
• NCBI Accession #: NP_001614.3
• NCBI GenBank Nucleotide #: NM_001623.3
• UniProt Accession #: P55008; O43904; Q9UIV4; Q9UKS9; A8K406
• Molecular Weight: 14,617 Da
• NCBI Official Full Name: allograft inflammatory factor 1 isoform 3
• NCBI Official Synonym Full Names: allograft inflammatory factor 1
• NCBI Official Symbol: AIF1
• NCBI Official Synonym Symbols: IBA1; IRT1; AIF-1; IRT-1
• NCBI Protein Information: allograft inflammatory factor 1; allograft inflammatory factor-1 splice variant Hara-1; interferon gamma responsive transcript; ionized calcium-binding adapter molecule 1; protein G1
• UniProt Protein Name: Allograft inflammatory factor 1
• UniProt Gene Name: AIF1
• UniProt Synonym Gene Names: G1; IBA1; AIF-1
• UniProt Entry Name: AIF1_HUMAN