Application Data
(C57BL/6 mouse bone marrow cells were stained with Rat Anti-mouse CD44-APC (AAA78661))
CD44/Pgp-1 Antibody | anti-Cd44 antibody
Rat Anti-Mouse CD44/Pgp-1-UNLB
Gene Names
Cd44; CD44A; METAA; RHAMM; MGC124941
Applications
Flow Cytometry, Functional Assay
Synonyms
CD44/Pgp-1; N/A; Rat Anti-Mouse CD44/Pgp-1-UNLB; Rat Anti-Mouse CD44/Pgp-1 - Purified, Unlabeled Antibody; Rat Anti-Mouse CD44/Pgp-1; anti-Cd44 antibody
Isotype
Rat (LOU/MN) IgG1 k
Clone Number
KM201
Specificity
Mouse CD44 (all isoforms); Mr 80-95 kDa
Form/Format
Supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2.
Applicable Applications for anti-Cd44 antibody
FCM/FACS (Flow Cytometry)
Immunogen
(C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2
Preparation and Storage
Store at 2-8°C.
Application Data
(C57BL/6 mouse bone marrow cells were stained with Rat Anti-mouse CD44-APC (AAA78661))
Application Data
(C57BL/6 mouse bone marrow cells were stained with Rat Anti-mouse CD44-APC (AAA78661))
Related Product Information for anti-Cd44 antibody
CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.
References
1. Miyake, K., K. L. Medina, S. Hayashi, S. Ono, T. Hamaoka, and P. W. Kincade. 1990. J. Exp. Med. 171:477.
2. Lesley, J., Q. He, K. Miyake, A. Hamann, R. Hyman, and P. W. Kincade. 1992. J. Exp. Med. 175:257.
3. Lazaar, A. L. and E. Pure. 1995. The Immunologist 3:19.
4. Culty, M., K. Miyake, P. W. Kincade, E. Sikorski, E. C. Butcher, C. Underhill, and E. T. Silorski. 1990. J. Cell Biol. 111:2765.
5. Wu, L., P. W. Kincade, and K. Shortman. 1993. Immunol. Lett. 38:69.
6. Sommer, F., M. Huber, M. Rollinghoff, and M. Lohoff. 1996. Int. Immunol. 7:1779.
7. Murakami, S., K. Miyake, R. Abe, and P. W. Kincade. 1991. J. Immunol. 146:1422.
8. He, Q., J. Lesley, R. Hyman, K. Ishihara, and P. W. Kincade. 1992. J. Cell Biol. 119:1711.
2. Lesley, J., Q. He, K. Miyake, A. Hamann, R. Hyman, and P. W. Kincade. 1992. J. Exp. Med. 175:257.
3. Lazaar, A. L. and E. Pure. 1995. The Immunologist 3:19.
4. Culty, M., K. Miyake, P. W. Kincade, E. Sikorski, E. C. Butcher, C. Underhill, and E. T. Silorski. 1990. J. Cell Biol. 111:2765.
5. Wu, L., P. W. Kincade, and K. Shortman. 1993. Immunol. Lett. 38:69.
6. Sommer, F., M. Huber, M. Rollinghoff, and M. Lohoff. 1996. Int. Immunol. 7:1779.
7. Murakami, S., K. Miyake, R. Abe, and P. W. Kincade. 1991. J. Immunol. 146:1422.
8. He, Q., J. Lesley, R. Hyman, K. Ishihara, and P. W. Kincade. 1992. J. Cell Biol. 119:1711.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
CD44 antigen
NCBI Official Synonym Full Names
Cd44 molecule
NCBI Official Symbol
Cd44
NCBI Official Synonym Symbols
CD44A; METAA; RHAMM; MGC124941
NCBI Protein Information
CD44 antigen; PGP-1; PGP-I; HUTCH-I; ECMR-III; hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; phagocytic glycoprotein I; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; Cell surface glycoprotein CD44 (hyaluronate binding protein)
UniProt Protein Name
CD44 protein
UniProt Gene Name
Cd44
UniProt Synonym Gene Names
CD44
UniProt Entry Name
O08779_RAT
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Product Notes
The Cd44 cd44 (Catalog #AAA78661) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD44/Pgp-1 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the Cd44 cd44 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD44/Pgp-1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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