SDS-PAGE
Asporin (ASPN) Recombinant Protein | ASPN recombinant protein
Recombinant Human Asporin (ASPN)
Gene Names
ASPN; OS3; PLAP1; PLAP-1; SLRR1C
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Asporin (ASPN); Recombinant Human Asporin (ASPN); Asporin; Periodontal ligament-associated protein 1; PLAP-1; ASPN recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
33-380aa; Full Length of Mature Protein
Sequence
DMEDTDDDDDDDDDDDDDDEDNSLFPTREPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEMQPATFRCVLSRMSVQLGNFGM
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
SDS-PAGE
SDS-PAGE
Related Product Information for ASPN recombinant protein
Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins (By similarity). Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity.
Product Categories/Family for ASPN recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55.7 kDa
NCBI Official Full Name
asporin isoform 2 preproprotein
NCBI Official Synonym Full Names
asporin
NCBI Official Symbol
ASPN
NCBI Official Synonym Symbols
OS3; PLAP1; PLAP-1; SLRR1C
NCBI Protein Information
asporin; asporin proteoglycan; asporin (LRR class 1); small leucine-rich protein 1C; periodontal ligament associated protein 1
UniProt Protein Name
Asporin
UniProt Gene Name
ASPN
UniProt Synonym Gene Names
PLAP1; SLRR1C; PLAP-1
UniProt Entry Name
ASPN_HUMAN
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Product Notes
The ASPN aspn (Catalog #AAA18736) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 33-380aa; Full Length of Mature Protein. The amino acid sequence is listed below: DMEDTDDDDD DDDDDDDDDE DNSLFPTREP RSHFFPFDLF PMCPFGCQCY SRVVHCSDLG LTSVPTNIPF DTRMLDLQNN KIKEIKENDF KGLTSLYGLI LNNNKLTKIH PKAFLTTKKL RRLYLSHNQL SEIPLNLPKS LAELRIHENK VKKIQKDTFK GMNALHVLEM SANPLDNNGI EPGAFEGVTV FHIRIAEAKL TSVPKGLPPT LLELHLDYNK ISTVELEDFK RYKELQRLGL GNNKITDIEN GSLANIPRVR EIHLENNKLK KIPSGLPELK YLQIIFLHSN SIARVGVNDF CPTVPKMKKS LYSAISLFNN PVKYWEMQPA TFRCVLSRMS VQLGNFGM . It is sometimes possible for the material contained within the vial of "Asporin (ASPN), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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