Application Data
Myeloperoxidase (MPO) Peroxidation Assay Kit | MPO assay kit
Myeloperoxidase (MPO) Peroxidation Activity Fluorometric Assay Kit
Synonyms
Myeloperoxidase (MPO) Peroxidation; N/A; Myeloperoxidase (MPO) Peroxidation Activity Fluorometric Assay Kit; MPO assay kit
Samples
Serum, plasma and tissue samples
Detection Range
0.001 - 1.26 U/L
Sensitivity
0.001 U/L
Preparation and Storage
Store at -20 degree C. Valid for 12 months
Application Data
Application Data
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for MPO assay kit
Intended Uses: This kit can be used to detect Myeloperoxidase (MPO) Peroxidation activity in serum, plasma and tissue samples.
Principle of the Assay: Under the catalysis of peroxidase, hydrogen peroxide can oxidize the nonfluorescent probe into the fluorescent substance, and its fluorescence intensity is proportional to the total peroxidase activity in the sample. This kit specifically inhibits the peroxidase activity of MPO in the sample through an MPO enzyme inhibitor, thus distinguishing the peroxidase activity of MPO in the sample from that of other peroxidases.
Background/Introduction: Myeloperoxidase is a heme-containing cationic glycoprotein that belongs to the heme peroxidase family in mammals. MPO is a dimer formed by polymerization of two subunits. Each subunit contains a heavy chain and a light chain. MPO is abundant in the azuropathic granules of polymorphonuclear leukocytes (PMNLs) and a small number in monocytes and macrophages. Studies have shown that MPO plays an important role in the generation of oxidants and host defense in neutrophils and is closely related to the pathogenesis of many diseases, including cardiovascular disease, lung injury and cancer.
Principle of the Assay: Under the catalysis of peroxidase, hydrogen peroxide can oxidize the nonfluorescent probe into the fluorescent substance, and its fluorescence intensity is proportional to the total peroxidase activity in the sample. This kit specifically inhibits the peroxidase activity of MPO in the sample through an MPO enzyme inhibitor, thus distinguishing the peroxidase activity of MPO in the sample from that of other peroxidases.
Background/Introduction: Myeloperoxidase is a heme-containing cationic glycoprotein that belongs to the heme peroxidase family in mammals. MPO is a dimer formed by polymerization of two subunits. Each subunit contains a heavy chain and a light chain. MPO is abundant in the azuropathic granules of polymorphonuclear leukocytes (PMNLs) and a small number in monocytes and macrophages. Studies have shown that MPO plays an important role in the generation of oxidants and host defense in neutrophils and is closely related to the pathogenesis of many diseases, including cardiovascular disease, lung injury and cancer.
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Product Notes
The MPO (Catalog #AAA177769) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Myeloperoxidase (MPO) Peroxidation, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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