Activating Transcription Factor-3 Recombinant Protein | ATF3 recombinant protein
Recombinant Human Activating Transcription Factor-3
Purity
Greater than 90.0% as determined by Analysis by SDS-PAGE.
Synonyms
Activating Transcription Factor-3; N/A; Recombinant Human Activating Transcription Factor-3; Activating transcription factor 3; cyclic AMP-dependent transcription factor ATF-3; FLJ41705; ATF3 recombinant protein
Purity/Purification
Greater than 90.0% as determined by Analysis by SDS-PAGE.
Form/Format
ATF3 protein (1mg/ml) is supplied in 20mM Tris-HCL, pH-8, 2M Urea and 20% Glycerol.
ATF3 is supplied as a sterile filtered clear solution.
ATF3 is supplied as a sterile filtered clear solution.
Sequence
MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S
Source
E Coli
Preparation and Storage
Store at 4 degree C if entire vial will be used in 2-4 weeks. Store frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for ATF3 recombinant protein
Description: ATF3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 181 amino acids (1-181) and having a molecular mass of 20.6 kDa.The ATF3 is purified by proprietary chromatographic techniques.
Introduction: ATF3 belongs to the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. ATF3 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in numerous viral and cellular promoters. Multiple transcript variants encoding two different isoforms are known for this gene. The longer isoform represses transcription from promoters with ATF binding elements instead of activating it. The shorter isoform (deltaZip2) which stimulates transcription by sequestering inhibitory co-factors away from the promoter has no leucine zipper protein-dimerization motif and does not bind to DNA.
Introduction: ATF3 belongs to the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. ATF3 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in numerous viral and cellular promoters. Multiple transcript variants encoding two different isoforms are known for this gene. The longer isoform represses transcription from promoters with ATF binding elements instead of activating it. The shorter isoform (deltaZip2) which stimulates transcription by sequestering inhibitory co-factors away from the promoter has no leucine zipper protein-dimerization motif and does not bind to DNA.
Product Categories/Family for ATF3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cyclic AMP-dependent transcription factor ATF-3 isoform 1
NCBI Official Synonym Full Names
activating transcription factor 3
NCBI Official Symbol
ATF3
NCBI Protein Information
cyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3
UniProt Protein Name
Cyclic AMP-dependent transcription factor ATF-3
UniProt Gene Name
ATF3
UniProt Synonym Gene Names
cAMP-dependent transcription factor ATF-3
UniProt Entry Name
ATF3_HUMAN
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Product Notes
The ATF3 atf3 (Catalog #AAA38917) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S. It is sometimes possible for the material contained within the vial of "Activating Transcription Factor-3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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