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Bacillus Anthracis Recombinant Protein

Bacillus Anthracis (Anthrax) protein (Protective Antigen)

Synonyms
Bacillus Anthracis; N/A; Bacillus Anthracis (Anthrax) protein (Protective Antigen); Bacillus Anthracis Protein; Bacillus anthracis Protective Nicked Antigen; Anthrax Protein; Recombinant B Anthracis; Bacillus Anthracis recombinant protein
Ordering
Form/Format
Lyophilized from 10mM BIS-Tris propane, pH 8.5, with 1.25% trehalose.
Reconstitute in sterile 50% Glycerol or sterile distilled water to a final concentration of 1mg/ml. Addition of BSA may enhance stability.
Concentration
100ug lyophilized (varies by lot)
Sequence Length
129
Species
Viral
Grade
Recombinant
Preparation and Storage
Shipping: Blue Ice; After receipt, store at 4°C.
Related Product Information for Bacillus Anthracis recombinant protein
PA63 is the carboxyl-terminal 63- kDa fragment obtained by the proteolytic cleavage of the receptor-bound protective antigen (PA), one of the three proteins that comprise anthrax toxin. Unlike native PA, PA 63 oligomerizes to form a ring-shaped heptamer that binds up to three copies of EF and/or LF competitively and with high affinity (kDa ~1 nM). Whereas native PA persists on the cell surface, the heptamer is endocytosed, presumably because oligomerization aggregates anthrax toxin receptor. The endocytosed toxic complexes are trafficked to endosomal compartments where the low pH causes the PA63 heptamer to insert into the membrane and form a water-filled channel.
Product Categories/Family for Bacillus Anthracis recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
Major band at 63kDa, by SDS-PAGE
NCBI Official Full Name
Bacillus anthracis protective antigen, partial

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Product Notes

The Bacillus Anthracis (Catalog #AAA75323) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Bacillus Anthracis, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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