Biglycan ELISA Kit | BGN elisa kit

Human Biglycan PicoKine ELISA Kit

Cat. Num. AAA46117

• Gene Names: BGN; PGI; DSPG1; PG-S1; SLRR1A
• Reactivity: Human. There is no detectable cross-reactivity with other relevant proteins.
• Synonyms: Biglycan; N/A; Human Biglycan PicoKine ELISA Kit; BGN; Biglycan proteoglycan; Bone/cartilage proteoglycan I; Dermatan sulphate proteoglycan I; DSPG1; PG S1; PG-S1; PGI; PGS1_HUMAN; SLRR1A; Small leucine rich protein 1A; biglycan; BGN elisa kit

• Reactivity: Human. There is no detectable cross-reactivity with other relevant proteins.
• Sequence Length: 368
• Samples: Cell culture supernates, serum, plasma (heparin, EDTA) and tissue homogenates
• Assay Type: Sandwich
• Sensitivity: <10pg/ml

• Immunogen: NSO, D38-K368
• Intra-Assay Precision: Sample 1: n=16; Mean(ng/ml): 1.62; Standard deviation: 0.06; CV(%): 3.7 Sample 2: n=16; Mean(ng/ml): 2.91; Standard deviation: 0.157; CV(%): 5.4 Sample 3: n=16; Mean(ng/ml): 5.38; Standard deviation: 0.264; CV(%): 4.9
• Inter-Assay Precision: Sample 1: n=24; Mean(ng/ml): 1.52; Standard deviation: 0.062; CV(%): 4.1 Sample 2: n=24; Mean(ng/ml): 3.07; Standard deviation: 0.209; CV(%): 6.8 Sample 3: n=24; Mean(ng/ml): 6.34; Standard deviation: 0.33; CV(%): 5.2
• Assay Range: 156pg/ml-10,000pg/ml
• Preparation and Storage: Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Standard Curve (Sample)

(Human Biglycan PicoKine ELISA Kit standard curve)

Related Product Information for BGN elisa kit

Description: Sandwich ELISA kit of Quantitative Detection for Human Biglycan
Background: Biglycan (BGN) is a small leucine-rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. It is an important structural component of articular cartilage and participates in the assembly of the chondrocyte extracellular matrix through formation of protein interactions with type VI collagen and large proteoglycan aggregates. In humans, Biglycan is encoded by the BGN gene. It is mapped to Xq28. Biglycan is believed to play a role in the mineralisation of bone, and its core protein binds to the growth factors BMP-4 and influences its bioactivity. It has been reported that the presence of biglycan is necessary for BMP-4 to exert its effects on osteoblasts. There is also evidence that biglycan can bind to TGF-beta 1. In addition, Biglycan plays an important role in cell signaling.

NCBI and Uniprot Product Information

• NCBI GI #: 4502403
• NCBI GeneID: 633
• NCBI Accession #: NP_001702.1
• NCBI GenBank Nucleotide #: NM_001711.4
• UniProt Accession #: P21810; P13247; D3DWU3
• Molecular Weight: 41,654 Da
• NCBI Official Full Name: biglycan preproprotein
• NCBI Official Synonym Full Names: biglycan
• NCBI Official Symbol: BGN
• NCBI Official Synonym Symbols: PGI; DSPG1; PG-S1; SLRR1A
• NCBI Protein Information: biglycan; biglycan proteoglycan; bone/cartilage proteoglycan I; bone/cartilage proteoglycan-I; small leucine-rich protein 1A; dermatan sulphate proteoglycan I
• UniProt Protein Name: Biglycan
• UniProt Gene Name: BGN
• UniProt Synonym Gene Names: SLRR1A
• UniProt Entry Name: PGS1_HUMAN