2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-dATP-alpha-S) Biochemical

2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-dATP-alpha-S)

Cat. Num. AAA52701

• Purity: Typical purity is better than 98% (HPLC / UV / 259 nm) at time of quality control and packing. However, actual purity depends on storage and transport conditions. The product is not sterile and has not been tested for endotoxins.
• Synonyms: 2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-dATP-alpha-S); N/A; 2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-dATP-alpha-S) biochemical

• Specificity: Aqueous solution of the sodium salt (10 mM). Other saltforms of Sp-dATP-α-S are available upon request. Micromolar quantities are determined by UV at λ_max.When opening the tube please make sure that no liquid is lost within the cap. A short spin-down in a bench centrifuge is recommended before use.
• Purity/Purification: Typical purity is better than 98% (HPLC / UV / 259 nm) at time of quality control and packing. However, actual purity depends on storage and transport conditions. The product is not sterile and has not been tested for endotoxins.

• CAS No.: 80875-87-2
• Formula: C₁₀H₁₆N₅O₁₁P₃S (free acid)
• UV: _λmax259 nm / ε 15200 / pH 7
• Properties: 1)Increased metabolic stability compared to dATP; 2)useful for modulation of dATP-responsive receptors and determination of their stereospecificity; 3)accepted by DNA polymerase for incorporation of phosphorothioate into DNA; 4)useful for Pyrosequencing techniques
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Preparation and Storage: Sp-dATP-α-S is relatively stable when stored as aqueous solution in the freezer (-20° Celsius necessary, -80° recommended), however, at ambient temperature the compound slowly starts to decompose forming dATP and other nucleotide fragments. Thus, in order to maintain its original high quality, and especially if you want to avoid the presence of any dATP, it is recommended to allow thawing only before using the product. If you will not use up the vial with one application, please aliquot the contents of the vial in order to avoid repeated freeze/thaw cycles for the rest. When making such aliquots be sure to operate quickly and to freeze the vial again as soon as possible.

Application Data

(Sp-dATP-α-S)

Related Product Information for 2'- Deoxyadenosine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-dATP-alpha-S) biochemical

Sp-dATP-α-S is a modification of 2'-deoxyadenosine triphosphate (dATP), where one of the non-bridging oxygens in the S position of the ?-phosphate is replaced by sulfur. The suffix "p" indicates that R/S nomenclature refers to phosphorus. The corresponding Rp-isomer is offered as well (Cat. No.MBS256292).