Structure
(Rp-8-CPT-cAMPS, CAS 129735-01-9)
(+/-)8(9)-EE-14(Z)-E biochemical
(+/-)8(9)-EE-14(Z)-E
Purity
98%
Synonyms
(+/-)8(9)-EE-14(Z)-E; N/A; (+/-)8(9)-EE-14(Z)-E biochemical
Purity/Purification
98%
Solubility
DMF: 10 mg/mL
PBS (pH 7.2): 0.5 mg/mL
DMSO: 10 mg/mL
Ethanol: 10 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
PBS (pH 7.2): 0.5 mg/mL
DMSO: 10 mg/mL
Ethanol: 10 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Rp-8-CPT-cAMPS, CAS 129735-01-9)
Structure
(Rp-8-CPT-cAMPS, CAS 129735-01-9)
Structure
(Rp-8-CPT-cAMPS, CAS 129735-01-9)
Structure
(Rp-8-CPT-cAMPS, CAS 129735-01-9)
Related Product Information for (+/-)8(9)-EE-14(Z)-E biochemical
(+/-)14(15)-EE-8(Z)-E is a potent vasodilator in bovine coronary arteries. The synthesis of this analog involves the formation of the epoxide at the 14,15-double bond, however, epoxidation can also occur at the 8,9-double bond. (+/-)8(9)-EE-14(Z)-E is a minor product from the synthesis of (+/-)14(15)-EE-8(Z)-E. This compound has not been reported in the literature, and its biological activity is not known. It may serve as a tool to verify that the parent compound, (+/-)14(15)-EE-8(Z)-E, is pure and does not contain the 8,9-epoxy regioisomer.
References
1. Dostmann WR, et, al. Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J Biol Chem. 1990 Jun 25;265(18):10484-91.
2. Roscioni SS, et, al. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells. Respir Res. 2009 Sep 29;10(1):88.
3. Chaisakul J, et, al. In vivo and in vitro cardiovascular effects of Papuan taipan (Oxyuranus scutellatus) venom: Exploring sudden collapse". Toxicol Lett. 2012 Sep 3;213(2):243-8."
2. Roscioni SS, et, al. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells. Respir Res. 2009 Sep 29;10(1):88.
3. Chaisakul J, et, al. In vivo and in vitro cardiovascular effects of Papuan taipan (Oxyuranus scutellatus) venom: Exploring sudden collapse". Toxicol Lett. 2012 Sep 3;213(2):243-8."
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Product Notes
The (+/-)8(9)-EE-14(Z)-E (Catalog #AAA227173) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "(+/-)8(9)-EE-14(Z)-E, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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