Structure
(Microcolin B, CAS 141205-32-5)
Amyloid-beta (1-8, A2V) Peptide Biochemical
Amyloid-beta (1-8, A2V) Peptide
Purity
98%
Synonyms
Amyloid-beta (1-8, A2V) Peptide; N/A; Amyloid-beta (1-8, A2V) Peptide biochemical
Purity/Purification
98%
Solubility
DMSO: Soluble
<1mg/ml refers to the product slightly soluble or insoluble
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Microcolin B, CAS 141205-32-5)
Structure
(Microcolin B, CAS 141205-32-5)
Structure
(Microcolin B, CAS 141205-32-5)
Structure
(Microcolin B, CAS 141205-32-5)
Related Product Information for Amyloid-beta (1-8, A2V) Peptide biochemical
Amyloid-beta (1-8, A2V) is a truncated form of amyloid-beta (Abeta) that contains a valine to alanine substitution at position 2 of the Abeta numbering convention (Abeta A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V). An Abeta (1-40)(Abeta40) A2V peptide increases the production of Abeta and the rate and amount of amyloid fibril formation in vitro, effects that can be reduced by coincubation with wild-type Abeta40. Abeta40 and Abeta42 levels are increased in CHO cells expressing the Abeta A2V mutation and in fibroblasts derived from patients with the Abeta A2V mutation. As a homozygous mutation, Abeta A2V is correlated with Alzheimer's disease with distinctive pathological features, but disease does not develop in patients with a heterozygous Abeta A2V mutation.
References
1. Merritt B. Andrus, et al. Synthesis of Microcolin B, a Potent New Immunosuppressant Using an Efficient Mixed Imide Formation Reaction. J. Org. Chem. 1997, 62, 16, 5542-5549.
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Product Notes
The Amyloid-beta (1-8, A2V) Peptide (Catalog #AAA227290) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Amyloid-beta (1-8, A2V) Peptide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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