Structure
(9-cis-Vitamin A palmitate, CAS 34356-29-1)
Bcl-2-IN-2 biochemical
Bcl-2-IN-2
Purity
98%
Synonyms
Bcl-2-IN-2; N/A; 9-cis-Retinyl palmitate; Bcl-2-IN-2 biochemical
Purity/Purification
98%
CAS
2383085-86-5
Targets&IC50
Bcl-xL:43 nM (IC50), Bcl-2:0.034 nM (IC50)
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Bcl-2-IN-2 inhibits mutant Bcl-2-G101V with an IC 50 of 1.2 nM. Bcl-2-IN-2 inhibits RS4;11 cellular proliferation with an IC 50 of 1.9 nM[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(9-cis-Vitamin A palmitate, CAS 34356-29-1)
Structure
(9-cis-Vitamin A palmitate, CAS 34356-29-1)
Structure
(9-cis-Vitamin A palmitate, CAS 34356-29-1)
Structure
(9-cis-Vitamin A palmitate, CAS 34356-29-1)
Related Product Information for Bcl-2-IN-2 biochemical
Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC 50 of 0.034 nM and also inhibits Bcl-xL with an IC 50 of 43 nM, showing 1000-fold selectivity for Bcl-2 over Bcl-xL.
References
1. Y.?S. Kim, et al. Degradation of Vitamin A Palmitate in Corn Flakes During Storage. Journal of Food Science. Volume65, Issue7. October 2000.
2. GuangwenTang, et al. Formation of all-trans-retinoic acid and 13-cis-retinoic acid from all-trans-retinyl palmitate in humans. The Journal of Nutritional Biochemistry. Volume 2, Issue 4, April 1991, Pages 210-213.
2. GuangwenTang, et al. Formation of all-trans-retinoic acid and 13-cis-retinoic acid from all-trans-retinyl palmitate in humans. The Journal of Nutritional Biochemistry. Volume 2, Issue 4, April 1991, Pages 210-213.
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Product Notes
The Bcl-2-IN-2 (Catalog #AAA228387) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Bcl-2-IN-2, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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