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product-image-AAA227772_STRUCTURE13.gif Structure (FRM-024, CAS 2085780-87-4)

CAP18 biochemical

CAP18 (rabbit)

Purity
98%
Synonyms
CAP18; N/A; CAP18 (rabbit); CAP18 biochemical
Ordering
Purity/Purification
98%
CAS
152742-15-9
Targets&IC50
Gram-negative bacteria:20-100 nM (IC50), Gram-positive bacteria:130-200 nM (IC50)
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years

Structure

(FRM-024, CAS 2085780-87-4)

product-image-AAA227772_STRUCTURE13.gif Structure (FRM-024, CAS 2085780-87-4)

Structure

(FRM-024, CAS 2085780-87-4)

product-image-AAA227772_STRUCTURE15.gif Structure (FRM-024, CAS 2085780-87-4)
Related Product Information for CAP18 biochemical
CAP18 (rabbit) is a 37 amino acids antimicrobial peptide originally isolated from rabbit granulocytes. CAP18 (rabbit) has broad antimicrobial activity against both Gram-positive (IC 50, 130-200 nM) and Gram-negative (IC 50, 20-100 nM) bacteria. CAP18 (rabbit) has the potential for bacterial sepsis research.
References
1. Bursavich MG, et al. Discovery of the Oxadiazine FRM-024: A Potent CNS-Penetrant Gamma Secretase Modulator. J Med Chem. 2021 Oct 14;64(19):14426-14447.

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Product Notes

The CAP18 (Catalog #AAA227772) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CAP18, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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