Structure
((2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid, CAS 76549-02-5)
Cinnamtannin A2 Biochemical
Cinnamtannin A2
Purity
98%
Synonyms
Cinnamtannin A2; N/A; Cinnamtannin A2 biochemical
Purity/Purification
98%
CAS
86631-38-1
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Cinnamtannin A2 (10 mg/kg; i.p. for 30 days) ameliorates the level of KIM1 and NAGL in 5/6 nephractomized rats by regulating Nrf2- Keap1 pathway[2]. Cinnamtannin A2 (10 ug/kg; p.o.) increases the secretion of insulin and glucagon-like peptide-1 (GLP-1) in plasma of mice[1]. Cinnamtannin A2 (10 ug/kg; p.o.) significantly promotes phosphorylation of both IRB and IRS-1 in mice[1]. Animal Model: Male Sprague-Dawley rats (250-300 g) were induced chronic renal failure (CRF) by removing the kidneys[2]. Dosage: 10 mg/kg. Administration: I.p. for 30 days. Result: Ameliorated the altered level of creatinine, blood urea nitrogen, Neutrophil gelatinase-associated lipocalin, Kidney Injury Molecule-1 and cytokines in the serum and microalbuminurea. Reduced the oxidative stress level. Attenuated the altered expression of proteins involved in Nrf2-Keap1 pathway in the kidney tissue. Reduced the tubular injury score in the kidney tissue.
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
((2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid, CAS 76549-02-5)
Structure
((2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid, CAS 76549-02-5)
Structure
((2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid, CAS 76549-02-5)
Structure
((2S,3S)-3-Hydroxy-2-methyl-3-phenylpropanoic acid, CAS 76549-02-5)
Related Product Information for Cinnamtannin A2 biochemical
Cinnamtannin A2, a tetrameric procyanidin, can increases GLP-1 and insulin secretion in mice. Cinnamtannin A2 could upregulate the expression of corticotrophin releasing hormone. Cinnamtannin A2 exhibits antioxidant, anti-diabetic and nephroprotective effect.
Product Categories/Family for Cinnamtannin A2 biochemical
References
1. Casper DM, et al. Toward the development of a structurally novel class of chiral auxiliaries: diastereoselective aldol reactions of a (1R,2S)-ephedrine-based 3,4,5,6-tetrahydro-2H-1,3,4-oxadiazin-2-one. Org Lett. 2002 Oct 17;4(21):3739-42.
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Product Notes
The Cinnamtannin A2 (Catalog #AAA228924) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cinnamtannin A2, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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