Structure
(XJB-5-131, CAS 866404-31-1)
Dihydroisopimaric acid Biochemical
Dihydroisopimaric acid
Purity
98%
Synonyms
Dihydroisopimaric acid; N/A; Dihydroisopimaric acid biochemical
Purity/Purification
98%
CAS
5673-36-9
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Effects of these compounds (10 microM) on the membrane potential of HEKBKalphabeta1 were monitored by use of DiBAC(43), a voltage-sensitive dye. Dihydroisopimaric acid induces substantial membrane hyperpolarization. Dihydroisopimaric acid (1-10 microM) activates BKalphabeta1 in the direct measurement of BKalphabeta1 opening under whole-cell voltage clamp[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(XJB-5-131, CAS 866404-31-1)
Structure
(XJB-5-131, CAS 866404-31-1)
Structure
(XJB-5-131, CAS 866404-31-1)
Structure
(XJB-5-131, CAS 866404-31-1)
Related Product Information for Dihydroisopimaric acid biochemical
Dihydroisopimaric acid activates large conductance Ca 2+ activated K + (BK) channels alphabeta1 in the direct measurement of BKalphabeta1 opening under whole-cell voltage clamp.
References
1. Carlos A Macias, et al. Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock. Ann Surg. 2007 Feb;245(2):305-14.
2. Zhiyin Xun, et al. Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease. Cell Rep. 2012 Nov 29;2(5):1137-42.
3. Julie P Goff, et al. Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells. Exp Hematol. 2013 Nov;41(11):957-66.
2. Zhiyin Xun, et al. Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease. Cell Rep. 2012 Nov 29;2(5):1137-42.
3. Julie P Goff, et al. Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells. Exp Hematol. 2013 Nov;41(11):957-66.
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Product Notes
The Dihydroisopimaric acid (Catalog #AAA228768) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Dihydroisopimaric acid, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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