Glatiramer Acetate Biochemical

Glatiramer Acetate

Cat. Num. AAA24108

• Purity: 100%
• Synonyms: Glatiramer Acetate; N/A; Glatiramer Acetate biochemical

• Purity/Purification: 100%
• Form/Format: Supplied as an off-white solid

• Molecular Formula: C₉H₁₁NO₃ •C₆H₁₄N₂O₂•C₅H₉NO₄•C₃H₇NO₂
• Reconstitution: Reconstitute with sterile PBS to a concentration of ~1mg/ml.
• Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
• Preparation and Storage: Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C.

Structure

(Structure of AAA24108L-Alanine polymer with L-Glutamic Acid L-Lysine L-Tyrosine Acetate ; L-Tyrosine polymer with L-Alanine L-Glutamic Acid L-Lysine Acetate; 511: PN: WO2010103292 PAGE: 64 claimed sequence; Cop 1; Copaxone; Copolymer 1; L-Glutamic Acid peptide with L-Alanine L-Lysine L-Tyrosine Acetate Salt; Protiramer; TV 5010)

Related Product Information for Glatiramer Acetate biochemical

Glatiramer (acetate) is a mixture of synthetic polycpeptides composed of four amino acids found in myelin basic protein (MBP): L-Alanine, L-glutamic acid, L-lysine, and L-tyrosine. It prevents MBP from binding to MHC class II molecules in the periphery and induces the production of immunomodulatory molecules considered to be anti-inflammatory. 1 It aslso increases proliferation of oligodendrocyte and neuronal precursor cells in the central nervous system of mice. Formulations containing Glatiramer (acetate) are used to treat patients with multiple sclerosis, particular the relapsing-remiting type.

Glatiramer acetate is a random basic synthetic copolymere of L-alanine, L-Lysine, L-glutamic acid and L-tyrosine in a molar ratio of 6:1.9:4.7:1. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis.

L-alanine: C₃H₇NO₂
L-lysine: C₆H₁₄N₂O₂
L-glutamic acid: C₅H₉NO₄
L-tyrosine: C₉H₁₁NO₃

Product Categories/Family for Glatiramer Acetate biochemical

Biochemicals; Biochem-Amino Acids