Structure
(rCRAMP (rat), CAS 376364-38-4)
IQZ23 biochemical
IQZ23
Purity
98%
Synonyms
IQZ23; N/A; IQZ23 biochemical
Purity/Purification
98%
CAS
2415643-79-5
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
IQZ23 (20 mg/kg, i.p.) treatment significantly reverses high fat and cholesterol diet (HFC)- induced body weight increases and accompanying clinical symptoms of obesity in mice but without indicative toxicity[1]. IQZ23 exhibits moderate terminal elimination half-lives (rat 4.2+/-0.3 h) and Cmax (rat 37.1+/-7.0 ng/mL) following oral administration (rat 5 mg/kg)[1]. IQZ23 exhibits terminal elimination half-lives (rat 4.4+/-0.4 h) following intravenous administration (rat 2 mg/kg)[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(rCRAMP (rat), CAS 376364-38-4)
Structure
(rCRAMP (rat), CAS 376364-38-4)
Structure
(rCRAMP (rat), CAS 376364-38-4)
Structure
(rCRAMP (rat), CAS 376364-38-4)
Related Product Information for IQZ23 biochemical
IQZ23 inhibits adipocyte differentiation via AMPK pathway activation. IQZ23 exerts a high efficacy in decreasing the triglyceride level (EC 50 =0.033 uM) in 3T3-L1 adipocytes. IQZ23 could be used for the research of obesity and related metabolic disorders.
References
1. S Termén, et al. Phylogeny, processing and expression of the rat cathelicidin rCRAMP: a model for innate antimicrobial peptides. Cell Mol Life Sci. 2003 Mar;60(3):536-49.
2. Peter Bergman, et al. The antimicrobial peptide rCRAMP is present in the central nervous system of the rat. J Neurochem. 2005 Jun;93(5):1132-40.
2. Peter Bergman, et al. The antimicrobial peptide rCRAMP is present in the central nervous system of the rat. J Neurochem. 2005 Jun;93(5):1132-40.
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Product Notes
The IQZ23 (Catalog #AAA228421) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IQZ23, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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