Structure
(Cl-PEG2-acid, CAS 170304-76-4)
Kdo2-Lipid A ammonium Biochemical
Kdo2-Lipid A ammonium
Purity
98%
Synonyms
Kdo2-Lipid A ammonium; N/A; Kdo2-Lipid A ammonium biochemical
Purity/Purification
98%
CAS
1246298-62-3
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
KDO2-Lipid A (i.t.) activates toll-like receptor 4 (TLR4) in rats[1]. Animal Model: Rats (Male Holzman Sprague-Dawley, 300-400 g)[1]. Dosage: 0.1 to 10 ug. Administration: I.T.; 0.1-10 ug; prior and 15, 30, 60, 90 and 120 min after injection of Kdo2-Lipid A. Result: Intrathecal injection of 1 ug Kdo2-Lipid A induces allodynia, and the animals appeared to be sick after i.t. injection of Kdo2-Lipid A.
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Cl-PEG2-acid, CAS 170304-76-4)
Structure
(Cl-PEG2-acid, CAS 170304-76-4)
Structure
(Cl-PEG2-acid, CAS 170304-76-4)
Structure
(Cl-PEG2-acid, CAS 170304-76-4)
Related Product Information for Kdo2-Lipid A ammonium biochemical
Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2.
References
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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Product Notes
The Kdo2-Lipid An ammonium (Catalog #AAA227540) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Kdo2-Lipid A ammonium, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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