Structure
(Amlodipine mesylate monohydrate, CAS 440358-84-9)
MitoTEMPOL biochemical
MitoTEMPOL
Purity
98%
Synonyms
MitoTEMPOL; N/A; MitoTEMPOL biochemical
Purity/Purification
98%
SMILES
[Br-].CC1(C)CC(CC(CC)N1[O])OCCCCC[P+](c1ccccc1c1ccccc1)c1ccccc1
Formula
C32H42BrNO2P
CAS
1101113-39-6
Solubility
Ethanol: 50 mg/mL
DMF: 50 mg/mL
DMSO: 50 mg/mL
PBS (pH 7.2): 10 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
DMF: 50 mg/mL
DMSO: 50 mg/mL
PBS (pH 7.2): 10 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Amlodipine mesylate monohydrate, CAS 440358-84-9)
Structure
(Amlodipine mesylate monohydrate, CAS 440358-84-9)
Structure
(Amlodipine mesylate monohydrate, CAS 440358-84-9)
Structure
(Amlodipine mesylate monohydrate, CAS 440358-84-9)
Related Product Information for MitoTEMPOL biochemical
MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO, MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling.
References
1. Gottwald-Hostalek U, Sun N, Barho C, Hildemann S. Management of Hypertension With a Fixed-Dose (Single-Pill) Combination of Bisoprolol and Amlodipine. Clin Pharmacol Drug Dev. 2017 Jan;6(1):9-18. doi: 10.1002/cpdd.309. Epub 2016 Oct 26. PubMed PMID: 27653022.
2. van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. Review. PubMed PMID: 9156957.
2. van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. Review. PubMed PMID: 9156957.
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Product Notes
The MitoTEMPOL (Catalog #AAA227091) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MitoTEMPOL, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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